Non-Anticoagulant Heparin Prodrug Loaded Biodegradable and Injectable Thermoresponsive Hydrogels for Enhanced Anti-Metastasis Therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201800409
Abstract: Metastasis is a pathogenic spread of cancer cells from the primary site to surrounding tissues and distant organs, making it one of the primary challenges for effective cancer treatment and the major cause of cancer… read more here.
Keywords: non anticoagulant; anti metastasis; metastasis; cancer ... See more keywords
Enhanced anti‐tumor and anti‐metastasis efficacy against breast cancer with an intratumoral injectable phospholipids‐based phase separation gel co‐loaded with 5‐fluotouracil and magnesium oxide by neutralizing acidic microenvironment
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.05.072
Abstract: Graphical abstract Figure. No caption available. ABSTRACT Traditional chemotherapy against breast cancer usually accompanied with metastasis. Thus, it is significant to enhance anti‐tumor and anti‐metastasis efficacy simultaneously. The extracellular environment of most tumors is acidic… read more here.
Keywords: tumor; metastasis efficacy; anti metastasis; metastasis ... See more keywords
Uncovering the anti-metastasis effects and mechanisms of capsaicin against hepatocellular carcinoma cells by metabolomics
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2019.103431
Abstract: Abstract Capsaicin, a kind of alkaloid from pepper cortex, has extensive anti-tumor activities. However, the anti-metastasis effects and mechanisms of capsaicin against hepatocellular carcinoma (HCC) have not been deeply studied so far. In the present… read more here.
Keywords: effects mechanisms; mechanisms capsaicin; anti metastasis; metastasis effects ... See more keywords
Low molecular weight heparin-based reduction-sensitive nanoparticles for antitumor and anti-metastasis of orthotopic breast cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials science"
DOI: 10.1039/c8bm00486b
Abstract: Tumor metastasis has become a major obstacle for the clinical treatment of malignant breast cancer. Thus, a delivery system capable of both antitumor and anti-metastasis efficacy is desired. In this work, a low molecular weight… read more here.
Keywords: breast; dox cllhc2; antitumor anti; anti metastasis ... See more keywords
Unlocking the potential of iridium and ruthenium arene complexes as anti-tumor and anti-metastasis chemotherapeutic agents.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of inorganic biochemistry"
DOI: 10.2139/ssrn.4223287
Abstract: It is a major challenge to design novel multifunctional metal-based chemotherapeutic agents for anti-tumor and anti-metastasis applications. Two complexes (OA-Ir and OA-Ru) were synthesized via CuAAC (copper-catalyzed azide-alkyne cycloaddition) reaction from nontoxic Ir-N3 or Ru-N3… read more here.
Keywords: metastasis; anti tumor; tumor anti; arene ... See more keywords
ATRA Entrapped in DSPC Liposome Enhances Anti-metastasis Effect on Lung and Liver During B16F10 Cell Line Metastasis in C57BL6 Mice.
Sign Up to like & getrecommendations! Published in 2017 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520616666160927103458
Abstract: BACKGROUND The high mortality rate of lung cancer is highly associated with faster metastasis spread. All Trans Retinoic Acid (ATRA), being the first choice drug for leukemia therapy is now under intense study for its… read more here.
Keywords: cell line; b16f10; anti metastasis; metastasis ... See more keywords
Ethyl P-Methoxycinnamate: An Active Anti-Metastasis Agent and Chemosensitizer Targeting NFκB from Kaempferia galanga for Melanoma Cells
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12030337
Abstract: The most common type of skin cancer is melanoma. While significant advances in chemotherapy have occurred in a few instances, only marginal progress has been made in treating metastatic melanoma. Natural medicine has traditionally been… read more here.
Keywords: ethyl methoxycinnamate; kaempferia galanga; anti metastasis; melanoma ... See more keywords
Mitochondria-Targeted Delivery of Camptothecin Based on HPMA Copolymer for Metastasis Suppression
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14081534
Abstract: Poor anti-metastasis effects and side-effects remain a challenge for the clinical application of camptothecin (CPT). Mitochondria can be a promising target for the treatment of metastatic tumors due to their vital roles in providing energy… read more here.
Keywords: metastasis; anti metastasis; dea cpt; cpt mitochondria ... See more keywords
Anti-proliferative and anti-metastasis effects of ten oligostilbenes from the seeds of Paeonia suffruticosa on human cancer cells.
Sign Up to like & getrecommendations! Published in 2017 at "Oncology letters"
DOI: 10.3892/ol.2017.5982
Abstract: Paeonia suffruticosa from the section Moutan of the genus Paeonia is an important Chinese medicinal herb. In our previous study, 10 oligostilbenes from the seeds of P. suffruticosa, including trans-resveratrol and its dimers and trimers,… read more here.
Keywords: anti proliferative; anti metastasis; metastasis effects; cancer ... See more keywords