Clinical Translation of [68Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-018-01302-5
Abstract: PurposeMacrophage mannose receptor (MMR, CD206) expressing tumor-associated macrophages (TAM) are protumorigenic and was reported to negatively impact therapy responsiveness and is associated with higher chances of tumor relapse following multiple treatment regimens in preclinical tumor models.… read more here.
Keywords: nota anti; anti mmr; mmr sdab; mmr ... See more keywords
The Postmodern Medical Paradigm: A Case Study of Anti-MMR Vaccine Arguments
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DOI: 10.1080/10570314.2018.1510136
Abstract: This essay analyzes the arguments of the antivaccination movement, arguing that many analysts have misdiagnosed the root causes of vaccine skepticism. It is no longer productive for argumentation scholars to discount scientific skepticism as simply… read more here.
Keywords: paradigm case; medical paradigm; postmodern medical; anti mmr ... See more keywords
In vivo Visualization of M2 Macrophages in the Myocardium After Myocardial Infarction (MI) Using 68Ga-NOTA-Anti-MMR Nb: Targeting Mannose Receptor (MR, CD206) on M2 Macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.889963
Abstract: Introduction and Objectives Wound healing after myocardial infarction (MI) is a dynamic and complex multiple phase process, and a coordinated cellular response is required for proper scar formation. The current paradigm suggests that pro-inflammatory monocytes… read more here.
Keywords: cd206; 68ga nota; anti mmr; nota anti ... See more keywords
Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting
Sign Up to like & getrecommendations! Published in 2023 at "Theranostics"
DOI: 10.7150/thno.77560
Abstract: Rationale: Nanobodies (Nbs) have emerged as an elegant alternative to the use of conventional monoclonal antibodies in cancer therapy, but a detailed microscopic insight into the in vivo pharmacokinetics of different Nb formats in tumor-bearers… read more here.
Keywords: anti mmr; microscopy; tumor; macrophage ... See more keywords