Abstract 1071: Efficacy of trifluridine/tipiracil + anti-mouse PD-1 antibody combination on mouse colorectal cancer model and related tumor immunomodulatory effects
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DOI: 10.1158/1538-7445.am2017-1071
Abstract: Background: Trifluridine/tipiracil (FTD/TPI) is an oral nucleoside antitumor agent that is composed of trifluridine and tipiracil hydrochloride at a molecular ratio of 1:0.5. Checkpoint-blockade immunotherapies are particularly effective in patients with tumor T cell infiltrations.… read more here.
Keywords: anti mouse; mouse antibody; ftd tpi;
Assessment of Therapeutic Effects of Combined Treatment With Cisplatin and Anti-mouse Programmed Death (PD)-1 Antibody in a Mouse Urothelial Cancer Model
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DOI: 10.21873/anticanres.16938
Abstract: Background/Aim: The therapeutic impact of combination treatment with an immune checkpoint inhibitor (ICI) and chemotherapeutic agent on patients with urothelial cancer (UC) remains controversial. Therefore, the present study investigated differences in the therapeutic effects of… read more here.
Keywords: treatment; cisplatin; antibody; dose cisplatin ... See more keywords
Epitope Mapping of Anti-Mouse CCR3 Monoclonal Antibodies Using Flow Cytometry
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DOI: 10.3390/antib11040075
Abstract: The CC chemokine receptor 3 (CCR3) is a receptor for CC chemokines, including CCL5/RANTES, CCL7/MCP-3, and CCL11/eotaxin. CCR3 is expressed on the surface of eosinophils, basophils, a subset of Th2 lymphocytes, mast cells, and airway… read more here.
Keywords: flow cytometry; mouse ccr3; c3mab; anti mouse ... See more keywords