Açaí (Euterpe oleracea Mart.) as a Potential Anti-neuroinflammatory Agent: NLRP3 Priming and Activating Signal Pathway Modulation.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular neurobiology"
DOI: 10.1007/s12035-021-02394-x
Abstract: Neurological disorders have been demonstrated to be associated with mitochondrial dysfunction. This impairment may lead to oxidative stress and neuroinflammation, specifically promoted by NLRP3 expression. Açaí (Euterpe oleracea Mart.) has been studied in this field,… read more here.
Keywords: agent; modulation; oleracea mart; nlrp3 priming ... See more keywords
Anti-neuroinflammatory effects of tryptanthrin from Polygonum tinctorium Lour. in lipopolysaccharide-stimulated BV2 microglial cells
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Pharmacal Research"
DOI: 10.1007/s12272-018-1020-8
Abstract: This study was conducted to isolate the anti-neuroinflammatory component(s) in the 80% EtOH extract of P. tinctoria, and to investigate underlying molecular mechanism of the anti-neuroinflammatory component(s) in LPS-induced BV2 microglial cells. To isolate the… read more here.
Keywords: bv2 microglial; stimulated bv2; neuroinflammatory effects; anti neuroinflammatory ... See more keywords
NO inhibitory constituents as potential anti-neuroinflammatory agents for AD from Blumea balsamifera.
Sign Up to like & getrecommendations! Published in 2018 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2017.12.008
Abstract: Our continuous search for new nitric oxide (NO) inhibitory substances as anti-neuroinflammatory agents for AD resulted in the isolation of one new labdane diterpenoid and three new guaiane sesquiterpenoids, as well as ten known compounds… read more here.
Keywords: inhibitory constituents; anti neuroinflammatory; blumea balsamifera; neuroinflammatory agents ... See more keywords
Nitric oxide inhibitory limonoids as potential anti-neuroinflammatory agents from Swietenia mahagoni.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.11.012
Abstract: Recent studies have revealed that there is a close relationship between neuroinflammation and Alzheimer's disease (AD) and compounds with anti-neuroinflammatory effects are potentially useful for the treatment of AD. A phytochemical investigation to obtain new… read more here.
Keywords: oxide inhibitory; swietenia mahagoni; anti neuroinflammatory; inhibitory limonoids ... See more keywords
N-salicyloyl tryptamine derivatives as potential therapeutic agents for Alzheimer's disease with neuroprotective effects.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105255
Abstract: Alzheimer's disease (AD) has become a serious threat to the developed nations with burgeoning patients and annual costs on health care system in modern society. Neuroinflammation, as one of the specific biochemical factors in the… read more here.
Keywords: neuroprotective effects; tryptamine derivatives; alzheimer disease; anti neuroinflammatory ... See more keywords
Anti-neuroinflammatory and antioxidant phenylpropanoids from Chinese olive.
Sign Up to like & getrecommendations! Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2019.02.031
Abstract: Chinese olive is served as a famous fruit and traditional herb in China. In this study, the anti-neuroinflammatory and antioxidant phytochemicals of Chinese olive fruits were investigated. Three new phenylpropanoids (2, 6, 19), together with… read more here.
Keywords: neuroinflammatory antioxidant; antioxidant phenylpropanoids; phenylpropanoids chinese; anti neuroinflammatory ... See more keywords
Structural characterization and anti-neuroinflammatory activity of a heteropolysaccharide isolated from the rhizomes of Polygala tenuifolia
Sign Up to like & getrecommendations! Published in 2020 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2020.112792
Abstract: Abstract Polygala tenuifolia Willd. is a vital industrial-export plant in Southeast Asia, particularly China. The rhizomes of P. tenuifolia are known for their nootropic and cognition-improving effects. As such, they have been widely used in… read more here.
Keywords: ptp70; polygala tenuifolia; neuroinflammatory activity; anti neuroinflammatory ... See more keywords
Oxymatrine exhibits anti-neuroinflammatory effects on Aβ1-42-induced primary microglia cells by inhibiting NF-κB and MAPK signaling pathways.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.105686
Abstract: Oxymatrine (OMT), isolated from Sophora flavescens or Sophora alopecuroides, possesses various pharmacological and biological activities, including anti-inflammatory, anti-oxidant, and anti-diabetic properties. Microglia cells, the resident immune cells in the central nervous system (CNS), play a… read more here.
Keywords: primary microglia; exhibits anti; microglia cells; neuroinflammatory effects ... See more keywords
Anti-neuroinflammatory and antioxidant phenols from mulberry fruit (Morus alba L.)
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DOI: 10.1016/j.jff.2020.103914
Abstract: Abstract Mulberry (Morus alba L.) fruit is a delicious, fleshy, succulent berry, which is served as a famous fruit in many countries and as traditional herb in China. In our current study, three new (1,… read more here.
Keywords: neuroinflammatory antioxidant; phenols mulberry; mulberry fruit; fruit ... See more keywords
Q43, a new triterpenoid extracted from Chinese acorn, exhibits pronounced anti-neuroinflammatory activity through the MAPK and NF-κB pathways
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2021.104566
Abstract: Abstract Chinese acorn was widely used as a food supplement in eastern Asia. Q43 is a new anti-neuroinflammatory triterpenoid extracted from Chinese acorn. Our aim was to study the anti-neuroinflammatory mechanisms of Q43 using BV2… read more here.
Keywords: anti neuroinflammatory; triterpenoid extracted; extracted chinese; chinese acorn ... See more keywords
Potential in vitro anti-neuroinflammatory sterols from mango fruits (Mangifera indica L.)
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DOI: 10.1016/j.jff.2021.104576
Abstract: Abstract Mango is one of the most popular fruit in tropical and subtropical regions of the world. In this study, previously undescribed two sterols (1–2) and one terpenoid (10), as well as ten known phytochemicals… read more here.
Keywords: anti neuroinflammatory; potential vitro; vitro anti; sterols mango ... See more keywords