Anti-nociceptive effect of stigmasterol in mouse models of acute and chronic pain
Sign Up to like & getrecommendations! Published in 2017 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-017-1416-x
Abstract: Stigmasterol is a common sterol found in plants, but the anti-nociceptive effect of this compound and its mechanism of action are not fully explored. Thus, in the present study, the anti-nociceptive effect of stigmasterol was… read more here.
Keywords: effect stigmasterol; stigmasterol; anti nociceptive; nociceptive effect ... See more keywords
Positive allosteric modulation of the cannabinoid type-1 receptor (CB1R) in periaqueductal gray (PAG) antagonizes anti-nociceptive and cellular effects of a mu-opioid receptor agonist in morphine-withdrawn rats.
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05650-5
Abstract: Opioid drugs are a first-line treatment for severe acute pain and other chronic pain conditions, but long-term opioid drug use produces opioid-induced hyperalgesia (OIH). Co-administration of cannabinoids with opioid receptor agonists produce anti-nociceptive synergy, but… read more here.
Keywords: opioid receptor; morphine; anti nociceptive; receptor ... See more keywords
Sphenodesme involucrata var. paniculata (C.B. Clarke) Munir.: Chemical characterization, anti-nociceptive and anti-inflammatory activities of methanol extract of leaves.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2018.06.035
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Sphenodesme involucrata var. paniculata (C. B. Clarke) Munir is native as well as endemic to South India. Its leaves are used in folklore medicine to treat pain and rheumatism. OBJECTIVE This study was… read more here.
Keywords: anti inflammatory; sphenodesme involucrata; effect; involucrata var ... See more keywords
Antipyretic and anti-nociceptive effects of methanol extract of leaves of Fimbristylis miliacea in mice model.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2019.112080
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Fimbristylis miliacea (L.) Vahl (Cyperaceae) is a grass like herb usually grows as a weed in rice fields and is mainly distributed in tropical or sub-tropical countries of south and south-east Asia, central… read more here.
Keywords: effects methanol; nociceptive effects; antipyretic anti; anti nociceptive ... See more keywords
Bupleurum falcatum L. alleviates nociceptive and neuropathic pain: Potential Mechanisms of Action.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2021.113990
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE In Iranian folkloric medicine, Bupleurum falcatum L. (Chinese Thoroughwax) has been used as a selective analgesic remedy for several centuries. OBJECTIVE The current research was conducted to explore the anti-nociceptive and anti-allodynic action… read more here.
Keywords: bupleurum falcatum; anti nociceptive; neuropathic pain; pain ... See more keywords
BotAF, a new Buthus occitanus tunetanus scorpion toxin, produces potent analgesia in rodents
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DOI: 10.1016/j.toxicon.2018.01.003
Abstract: &NA; This work reports the purification of new potent scorpion neuropeptide, named BotAF, by an activity‐guided screening approach. BotAF is a 64‐residue long‐chain peptide that shares very high similarity with the original &bgr;‐like scorpion toxin… read more here.
Keywords: scorpion; anti nociceptive; botaf; activity ... See more keywords
Evaluation of Anti-inflammatory and Anti-nociceptive Potentials of Andrographolide and Forskolin: In vivo Studies
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biologically Active Products from Nature"
DOI: 10.1080/22311866.2018.1526650
Abstract: Abstract Andrographis paniculata and Coleus forskholii are medicinal plants, used in traditional Ayurveda systems and owe therapeutic properties due to their bioactive ingredients andrographolide and forskolin respectively. In the present investigation, both these molecules were… read more here.
Keywords: anti inflammatory; evaluation anti; andrographolide forskolin; anti nociceptive ... See more keywords
Hydrogen sulfide attenuates diabetic neuropathic pain through NO/cGMP/PKG pathway and μ-opioid receptor
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Biology and Medicine"
DOI: 10.1177/1535370220918193
Abstract: Diabetic neuropathic pain is a frequent complication of diabetic neuropathy. The specific manifestations of diabetic neuropathic pain include spontaneous pain and hyperalgesia, which seriously affect the quality of life of patients. Previous publications have shown… read more here.
Keywords: pain; diabetic neuropathic; pkg; anti nociceptive ... See more keywords
Assessment of Iris albicans lange as potential antimicrobial and analgesic agent
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DOI: 10.1371/journal.pone.0280127
Abstract: Objective of the present work was to evaluate the presence of phytochemical constituents and pharmacological activities (antimicrobial and anti-nociceptive) of crude extract isolated from Iris albicans and its corresponding fractions. Extraction was made with methanol… read more here.
Keywords: iris albicans; lange potential; antimicrobial analgesic; anti nociceptive ... See more keywords
Anti-Nociceptive and Anti-Inflammatory Activities of the Ethyl Acetate Extract of Belamcanda chinensis (L.) Redouté in Raw 264.7 Cells in vitro and Mouse Model in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pain Research"
DOI: 10.2147/jpr.s353357
Abstract: Purpose Inflammation and accompanying pain is a common global health problem that seriously affects human quality of life worldwide. Here, we aimed to investigate the anti-nociceptive and anti-inflammatory activities of the ethyl acetate extract of… read more here.
Keywords: inflammatory activities; nociceptive anti; anti nociceptive; anti inflammatory ... See more keywords
Assessment of the anti-nociceptive effects of fetal ventral mesencephalic tissue allografts in a rat model of hemi-Parkinson’s disease using fMRI
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.948848
Abstract: Extensive studies showed increased subjective pain sensitivity in Parkinson’s disease (PD), which appeared to be partially reversed by dopaminergic (DA) treatment. Although cell replacement represents an attractive therapeutic strategy, its potential for PD-related hyperalgesia remains… read more here.
Keywords: anti nociceptive; effects fetal; rat model; nociceptive effects ... See more keywords