Health-related quality of life in survivors of advanced melanoma treated with anti-PD1-based immune checkpoint inhibitors.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.5967
Abstract: BACKGROUND Immune checkpoint inhibitors (ICIs) have significantly improved survival in advanced melanoma but are associated with immune-related adverse events (irAEs). This single center, cross-sectional survey aimed to describe the long-term symptom burden and impact on… read more here.
Keywords: advanced melanoma; health; checkpoint inhibitors; immune checkpoint ... See more keywords
OUTCOME OF CURATIVE RADIOTHERAPY FOR LOCALISED FOLLICULAR LYMPHOMA IN THE ERA OF 18F‐FDG PET‐CT STAGING: AN INTERNATIONAL COLLABORATIVE STUDY ON BEHALF OF ILROG
Sign Up to like & getrecommendations! Published in 2017 at "Hematological Oncology"
DOI: 10.1002/hon.2437_10
Abstract: also been approved as adjuvant therapy for high risk stage III melanoma (2015). Results regarding adjuvant therapy with either nivolumab or pembrolizumab are expected in 2018. Combinations: Further developments in the field of melanoma are… read more here.
Keywords: combination; lymphoma; anti pd1; radiotherapy localised ... See more keywords
A multi‐omic single cell sequencing approach to develop a CD8 T cell specific gene signature for anti‐PD1 response in solid tumors
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34218
Abstract: Immune checkpoint blockade (ICB) has led to durable clinical responses in multiple cancer types. However, biomarkers that identify which patients are most likely to respond to ICB are not well defined. Many putative biomarkers developed… read more here.
Keywords: cell; response; signature; anti pd1 ... See more keywords
Prognostic and theranostic 18F-FDG PET biomarkers for anti-PD1 immunotherapy in metastatic melanoma: association with outcome and transcriptomics
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-019-04411-7
Abstract: PurposeAn imaging-based stratification tool is needed to identify melanoma patients who will benefit from anti Programmed Death-1 antibody (anti-PD1). We aimed at identifying biomarkers for survival and response evaluated in lymphoid tissue metabolism in spleen… read more here.
Keywords: melanoma; anti pd1; fdg pet; 18f fdg ... See more keywords
High tumor mutational burden and T-cell activation are associated with long-term response to anti-PD1 therapy in Lynch syndrome recurrent glioblastoma patient
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02769-4
Abstract: Background Glioblastomas (GBMs) in patients harboring somatic or germinal mutations of mismatch-repair (MMR) genes exhibit a hypermutable phenotype. Here, we describe a GBM patient with increased tumor mutational burden and germline MMR mutations, treated using… read more here.
Keywords: pd1 therapy; cell; anti pd1; response ... See more keywords
Immune-related adverse events correlate with improved survival in patients undergoing anti-PD1 immunotherapy for metastatic melanoma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-018-2819-x
Abstract: BackgroundTherapeutic chances for metastatic melanoma have consistently changed over the last years with the advent of antibodies targeting the programmed cell death protein-1 (PD-1). Onset of immune-related adverse events (irAEs) during treatment can be a… read more here.
Keywords: related adverse; immune related; metastatic melanoma; anti pd1 ... See more keywords
Reverse immune suppressive microenvironment in tumor draining lymph nodes to enhance anti-PD1 immunotherapy via nanovaccine complexed microneedle
Sign Up to like & getrecommendations! Published in 2020 at "Nano Research"
DOI: 10.1007/s12274-020-2737-5
Abstract: The maturation of dendritic cells (DCs) and infiltration effector T cells in tumor-draining lymph node (tdLN) and tumor tissue are crucial for immunotherapy. Despite constructive progresses have been made with anti-programmed death-1 (anti-PD1) checkpoint blockade… read more here.
Keywords: draining lymph; anti pd1; immunotherapy; nanovaccine complexed ... See more keywords
Mélanomes primitifs localement avancés et inopérables en rémission complète après traitement néoadjuvant par anti-PD1 : 3 cas
Sign Up to like & getrecommendations! Published in 2017 at "Annales De Dermatologie Et De Venereologie"
DOI: 10.1016/j.annder.2017.09.057
Abstract: Introduction Les anti-programmed cell death 1 (anti-PD1) font desormais partie du traitement de premiere intention des melanomes metastatiques stade IV ou IIIC inoperables. En revanche, leur interet et efficacite dans les melanomes primitifs inextirpables ou… read more here.
Keywords: melanome; anti pd1; anti; par anti ... See more keywords
Immunothérapie par anti-PD1 et carcinomes épidermoïdes cutanés localement avancés : un futur proche ?
Sign Up to like & getrecommendations! Published in 2017 at "Annales De Dermatologie Et De Venereologie"
DOI: 10.1016/j.annder.2017.09.250
Abstract: Introduction Le carcinome epidermoide cutane (CEC) est un des cancers les plus frequents, avec un taux d’incidence en augmentation. Bien que le traitement chirurgical permette dans la majorite des cas d’obtenir la guerison, une extension… read more here.
Keywords: anti pd1; par; cec localement; localement avances ... See more keywords
Anti-PD1/PDL1 induced psoriasis.
Sign Up to like & getrecommendations! Published in 2017 at "Current problems in cancer"
DOI: 10.1016/j.currproblcancer.2017.10.003
Abstract: BACKGROUND Immune checkpoint inhibitors are novel agents approved for the treatment of late-stage malignancies. Despite its important clinical benefits, checkpoint inhibition is associated with a unique spectrum of side effects known as immune-related adverse events.… read more here.
Keywords: psoriasis; treatment; anti pd1; pd1 pdl1 ... See more keywords
Inhibition of IL-18-mediated myeloid derived suppressor cell accumulation enhances anti-PD1 efficacy against osteosarcoma cancer
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Bone Oncology"
DOI: 10.1016/j.jbo.2017.10.002
Abstract: Myeloid derived suppressor cells (MDSC) are very important in tumor immune evasion and they dramatically increased in peripheral blood of patients with osteosarcoma cancer. The association between MDSC and various cytokines has been studied in… read more here.
Keywords: anti pd1; derived suppressor; osteosarcoma cancer; blood ... See more keywords