Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease
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DOI: 10.1073/pnas.2123487119
Abstract: Significance Immunotherapy has been proposed for neurodegenerative disorders including Alzheimer’s disease. Recent reports using antibodies against poly-GA or active immunization suggested similar immunotherapy in ALS/FTD caused by repeat expansion in the C9orf72 gene. Here, we… read more here.
Keywords: comprehensive evaluation; human derived; evaluation human; anti poly ... See more keywords