Isolation and characterization of flavonoid derivatives with anti-prostate cancer and hepatoprotective activities from the flowers of Hosta plantaginea (Lam.) Aschers.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.112685
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE The flower of Hosta plantaginea (Lam.) Aschers (Liliaceae) is a traditional medicinal material in Mongolian medicine for treating sore throat, hoarseness, pulmonary fever, and toxic fever in folk. The present work investigated anti-prostate… read more here.
Keywords: lam aschers; plantaginea lam; hepatoprotective activities; prostate cancer ... See more keywords
Design, Synthesis and Biological Evaluation of 1-methyl-1H-pyrazole-5-Carboxamide Derivatives as Novel Anti-Prostate Cancer Agents.
Sign Up to like & getrecommendations! Published in 2021 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520621666210202162953
Abstract: BACKGROUND The androgen receptor (AR) signaling functions is a critical driving force for the progression of prostate cancer (PCa) to bring about anti-prostate cancer agents, and AR has been proved to be an effective therapeutic… read more here.
Keywords: prostate cancer; novel anti; anti prostate; cancer ... See more keywords
Anti-prostate cancer metabolites from the soil-derived Aspergillus neoniveus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1006062
Abstract: Prostate cancer (PCa) ranks as one of the most commonly diagnosed malignancies worldwide. Toxicity, lack of clinical efficacy, and development of resistance phenotypes are the main challenges in the control of prostate malignancies. Notably, castration-resistance… read more here.
Keywords: prostate cancer; aspergillus neoniveus; prostate; soil derived ... See more keywords
Design, Synthesis and In-Silico Studies of Novel Chalcones as Anti-Prostate Cancer and Cathepsin B Inhibitors -
Sign Up to like & getrecommendations! Published in 2017 at "journal of applied pharmaceutical science"
DOI: 10.7324/japs.2017.70702
Abstract: The high mortality rate in prostate cancer patients could be mainly attributed to the invasiveness and metastasis of advanced prostate cancer. Cathepsin B, a lysosomal cysteine, that proved to play a significant role in the… read more here.
Keywords: prostate cancer; cathepsin; cancer cathepsin; anti prostate ... See more keywords