Clinical significance of anti-Ro52 (TRIM21) antibodies in adult patients with connective tissue diseases.
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DOI: 10.1016/j.ejim.2021.04.020
Abstract: OBJECTIVES Clinical significance of anti-Ro52 antibodies in connective tissue diseases (CTD) is controversial. Anti-Ro52 antibodies might be associated with a more severe CTD phenotype, especially interstitial lung disease (ILD). The aims of this study were… read more here.
Keywords: ctd patients; ro52; ro52 antibodies; anti ro52 ... See more keywords
Anti-Ro60 and anti-Ro52/TRIM21: Two distinct autoantibodies in systemic autoimmune diseases.
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DOI: 10.1016/j.jaut.2021.102724
Abstract: As iconic and important diagnostic autoantibodies, anti-Ro60 and anti-Ro52/tri-partite motif-containing 21 (TRIM21) make a common appearance in a number of systemic autoimmune disorders such as systemic lupus erythematosus (SLE). These autoantibodies often co-exist together; yet… read more here.
Keywords: anti ro60; anti; ro60 anti; anti ro52 ... See more keywords
Anti-Ro52 antibodies are associated with the prognosis of adult idiopathic inflammatory myopathy-associated interstitial lung disease.
Sign Up to like & getrecommendations! Published in 2022 at "Rheumatology"
DOI: 10.1093/rheumatology/keac090
Abstract: OBJECTIVES In the present study, we aimed to assess the prevalence and clinical significance of anti-Ro52 antibodies in a cohort of patients with idiopathic inflammatory myopathy-associated interstitial lung disease (IIM-ILD) with different myositis-specific autoantibodies (MSAs).… read more here.
Keywords: anti ro52; ro52 antibodies; lung disease; interstitial lung ... See more keywords
THU0676 ANTI-RO/SS-A 52-KDA antibodies: a marker for lung fibrosis in rheumatic diseases
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.2890
Abstract: Background Lung fibrosis (LF) is a type of interstitial disease that leads to lung scarring, respiratory failure and later on, death. There are 2 main types of LF: idiopathic and secondary; and the prognosis is… read more here.
Keywords: fibrosis; trim21 antibodies; age; ro52 trim21 ... See more keywords
THU0614 Interstitial lung disease in patients with antisynthetase syndrome and anti-ro52 antibodies positive
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.3146
Abstract: Background Antisynthetase syndrome (ASS) is characterised by the presence of myositis, arthritis, interstitial lung disease (ILD), fever, Raynaud’s phenomenon and mechanical’s hand, in the presence of antisynthetase autoantibodies (AA), the most frequent being anti-Jo1, anti-PL7… read more here.
Keywords: ass; ro52; anti; anti ro52 ... See more keywords
AB1181 Anti-ro60 seropositivity determines epitope specificity of anti-ro52 antibodies in patients with autoimmune rheumatic and malignant diseases
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.6760
Abstract: Background Epitope mapping of anti-Ro52 antibodies (abs) has been extensively studied in patients with Sjögren’s syndrome (SjS) and systemic lupus erythematosus (SLE). Comprehensive epitope mapping in systemic sclerosis (SSc) or malignant diseases (MD), also associated… read more here.
Keywords: anti ro52; ro52 ro52; ro52pos ro60pos; ro52 ... See more keywords
AB0033 B regulatory cells positively correlate with antibodies against ss-a ro52 in systemic sclerosis
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.7186
Abstract: Background We and Japanese Investigators have shown that IL-10-producing regulatory B cells (B10 cells) are decreased in systemic sclerosis (SSc).1 2 Contrary to the Japanese, we did not find a negative correlation between B10 cells… read more here.
Keywords: bregs; ro52; ssc patients; anti ro52 ... See more keywords
Response to: ‘Comment on: ‘Anti-Ro52 autoantibodies are associated with interstitial lung disease and more severe disease in patients with juvenile myositis’ by Sabbagh S et al’ by Yang et al
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DOI: 10.1136/annrheumdis-2019-215693
Abstract: We are grateful for the interest in our work1 shown by Drs Yang and Liang. In their correspondence regarding this work,2 they raise concerns about (1) the association between anti-Ro52 autoantibodies and interstitial lung disease… read more here.
Keywords: lung disease; disease; interstitial lung; ro52 autoantibodies ... See more keywords
Clinical Significance of Different Profiles of anti-Ro Antibodies in Connective Tissue Diseases
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DOI: 10.1155/2023/9195157
Abstract: Objective Anti-Ro60 and anti-Ro52 antibodies are associated with different connective tissue diseases (CTDs). However, the clinical significance of anti-Ro antibodies is not always consistent among different global regions. The aim of this study was to… read more here.
Keywords: anti ro52; anti ro60; different profiles; patients anti ... See more keywords
Presentations and outcomes of interstitial lung disease and the anti-Ro52 autoantibody
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DOI: 10.1186/s12931-019-1231-7
Abstract: BackgroundDistinct clinical presentations of interstitial lung disease (ILD) with the myositis-specific antibodies, including anti-synthetase antibodies, are well-recognized. However, the association between ILD and the myositis-associated antibodies, including anti-Ro52, is less established. Our objectives were to… read more here.
Keywords: ro52; disease; interstitial lung; anti ro52 ... See more keywords
Diagnostic Utility of Separate Anti-Ro60 and Anti-Ro52/TRIM21 Antibody Detection in Autoimmune Diseases
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DOI: 10.3389/fimmu.2019.00444
Abstract: Anti-SS-A antibodies are often sought for in autoimmune diseases diagnosis. Two different target proteins have actually been identified: Ro52 and Ro60. Clinical and immunological associations seem different depending on anti-Ro52 or anti-Ro60 antibodies presence. However,… read more here.
Keywords: ro52; anti ro60; ro52 ro60; anti ro52 ... See more keywords