Abstract 1789: Pre-clinical studies to advance anti-ROR1 CAR-T cell therapy for metastatic prostate cancer
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DOI: 10.1158/1538-7445.am2023-1789
Abstract: Background: Alterations in WNT signaling are frequently associated with tumorigenesis and metastasis in many cancers including prostate cancer (PCa). The Wnt ligand, WNT5A, is required for normal prostate gland development and is increased in bone… read more here.
Keywords: cell; prostate cancer; anti ror1; zilovertamab ... See more keywords
Abstract LB218: Developing a bispecific anti-ROR1 antibody drug conjugate for hematological and solid tumor treatment
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DOI: 10.1158/1538-7445.am2023-lb218
Abstract: Developing a bispecific anti-ROR1 Antibody Drug Conjugate for hematological and solid tumor treatment Receptor tyrosine kinase ROR1 is a type I transmembrane protein belongs to the ROR family members. ROR1 is a receptor for Wnt… read more here.
Keywords: anti ror1; ror1; hematological solid; drug conjugate ... See more keywords