Using electronic health data to explore effectiveness of ICU EEG and anti-seizure treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of clinical and translational neurology"
DOI: 10.1002/acn3.51478
Abstract: OBJECTIVES The purpose of this study was to examine critical care continuous electroencephalography (cEEG) utilization and downstream anti-seizure treatment patterns, their association with outcomes, and generate hypotheses for larger comparative effectiveness studies of cEEG-guided interventions.… read more here.
Keywords: anti seizure; treatment; asm escalation; mortality ... See more keywords
Availability, affordability, and quality of essential anti‐seizure medication in Cambodia
Sign Up to like & getrecommendations! Published in 2021 at "Epilepsia Open"
DOI: 10.1002/epi4.12514
Abstract: Epilepsy is a major neurological disorder that requires long‐term medical treatment. Once epilepsy is diagnosed, people with epilepsy face many difficulties in accessing treatment (treatment gap). Our objective was to assess the situation regarding the… read more here.
Keywords: treatment; seizure medication; anti seizure; affordability quality ... See more keywords
An investigation of the effects of chronic zonisamide, sultiam, lacosamide, clobazam, and rufinamide anti‐seizure medications on foliculogenesis in ovarian tissue in prepubertal non‐epileptic rats
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Developmental Neuroscience"
DOI: 10.1002/jdn.10200
Abstract: We aimed to determine the morphological and histological effects of zonisamide, sultiam, lacosamide, clobazam, and rufinamide on ovarian folliculogenesis in rats. Sixty female Wistar rats were divided into six experimental groups as control, zonisamide, sultiam,… read more here.
Keywords: anti seizure; zonisamide sultiam; sultiam lacosamide; lacosamide clobazam ... See more keywords
Can We Anticipate and Prevent the Occurrence of Iatrogenic Psychiatric Events Caused by Anti-seizure Medications and Epilepsy Surgery?
Sign Up to like & getrecommendations! Published in 2021 at "Current topics in behavioral neurosciences"
DOI: 10.1007/7854_2021_228
Abstract: Psychiatric disorders and behavioral manifestations in patients with epilepsy have complex and multifactorial etiologies. The psychotropic properties of anti-seizure medications (ASMs) and psychiatric effects of epilepsy surgery can result in iatrogenic psychiatric symptoms or episodes… read more here.
Keywords: epilepsy surgery; anti seizure; iatrogenic psychiatric; seizure medications ... See more keywords
Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemical Research"
DOI: 10.1007/s11064-020-03017-y
Abstract: Focal epileptic seizures can in some patients be managed by inhibiting γ-aminobutyric acid (GABA) uptake via the GABA transporter 1 (GAT1) using tiagabine (Gabitril®). Synergistic anti-seizure effects achieved by inhibition of both GAT1 and the… read more here.
Keywords: bgt1; inhibition; gaba transporter; anti seizure ... See more keywords
Emergency First-Line Anti-Seizure Medication for Seizures and Status Epilepticus: What is Going Wrong, Doctor?
Sign Up to like & getrecommendations! Published in 2018 at "CNS Drugs"
DOI: 10.1007/s40263-018-0570-0
Abstract: Repetitive and prolonged seizures as well as status epilepticus represent life-threatening neurologic emergencies with serious cerebral and systemic sequela [1]. High morbidity and mortality associated with untreated or uncontrolled seizures call for emergency treatment including… read more here.
Keywords: seizure medication; status epilepticus; emergency; seizure ... See more keywords
T08. Early changes in responsive neurostimulator detection rates after introduction: Of anti-seizure drugs predict efficacy
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2018.04.009
Abstract: Introduction The responsive neurostimulation (RNS) system is used for cases of medically refractory focal epilepsy in which curative resection is not possible. Uniquely, the device provides long term ambulatory neurophysiologic data including counts of intracranial… read more here.
Keywords: detection; efficacy; long episodes; medication ... See more keywords
Anti-seizure medication correlated changes of cortical morphology in childhood epilepsy with centrotemporal spikes
Sign Up to like & getrecommendations! Published in 2021 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2021.106621
Abstract: To investigate the morphological changes of cerebral cortex correlating with anti-seizure medication in Childhood Epilepsy with Centrotemporal Spikes (CECTS), and their relationships with seizure control. This study included a total of 188 children, including 62… read more here.
Keywords: analysis; seizure medication; medication; childhood epilepsy ... See more keywords
Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti-seizure efficacy
Sign Up to like & getrecommendations! Published in 2018 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.09.025
Abstract: ABSTRACT Based on the potential role of Na‐K‐Cl cotransporters (NKCCs) in epileptic seizures, the loop diuretic bumetanide, which blocks the NKCC1 isoforms NKCC1 and NKCC2, has been tested as an adjunct with phenobarbital to suppress… read more here.
Keywords: bumetanide; inhibit nkcc1; brain; anti seizure ... See more keywords
An economic evaluation of vagus nerve stimulation as an adjunctive treatment to anti-seizure medications for the treatment of drug resistant epilepsy in the United States.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medical economics"
DOI: 10.1080/13696998.2023.2171230
Abstract: INTRODUCTION People with recurrent epileptic seizures are typically treated with anti-seizure medications (ASMs). Around a third of epilepsy patients fail to achieve an adequate response to ASMs and may be eligible to receive vagus nerve… read more here.
Keywords: seizure; anti seizure; vns; epilepsy ... See more keywords
The impact of anti-seizure medications on electroencephalogram (EEG) results.
Sign Up to like & getrecommendations! Published in 2023 at "Expert review of neurotherapeutics"
DOI: 10.1080/14737175.2023.2214315
Abstract: ABSTRACT Introduction Despite recent advances in neuroimaging and genetics, electroencephalography (EEG) continues to play a central role in the diagnosis and management of epilepsy. One application of EEG is called pharmaco-EEG. This technique is highly… read more here.
Keywords: anti seizure; impact anti; seizure medications; eeg ... See more keywords