Cladribine in combination with entinostat synergistically elicits anti-proliferative/anti-survival effects on multiple myeloma cells
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DOI: 10.1080/15384101.2018.1464849
Abstract: ABSTRACT Cladribine (2CdA), a synthetic purine analog interfering with DNA synthesis, is a medication used to treat hairy cell leukemia (HCL) and B-cell chronic lymphocytic leukemia. Entinostat, a selective class I histone deacetylase (HDAC) inhibitor,… read more here.
Keywords: anti proliferative; anti survival; cladribine entinostat; multiple myeloma ... See more keywords
Anti-Survival Effect of SI306 and Its Derivatives on Human Glioblastoma Cells
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DOI: 10.3390/pharmaceutics14071399
Abstract: Glioblastoma (GBM) is the most common adult brain tumor and, although many efforts have been made to find valid therapies, the onset of resistance is the main cause of recurrence. Therefore, it is crucial to… read more here.
Keywords: glioblastoma; effect; si306; anti survival ... See more keywords