Anti-transcription intermediary factor 1-gamma IgG2 isotype is associated with cancer in adult dermatomyositis: an ENMC multinational study.
Sign Up to like & getrecommendations! Published in 2022 at "Rheumatology"
DOI: 10.1093/rheumatology/keac577
Abstract: OBJECTIVE To assess the role of the anti-TIF1γ auto-antibody (aAb) IgG2 isotype as a biomarker of cancer in anti-TIF1γ aAb-positive adult dermatomyositis (DM). METHODS International multicentre retrospective study with the following inclusion criteria: i) diagnosis… read more here.
Keywords: igg2; adult; aab; anti tif1 ... See more keywords
Coexisting autoantibodies against transcription factor Sp4 are associated with decreased cancer risk in patients with dermatomyositis with anti-TIF1γ autoantibodies
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/ard-2022-222441
Abstract: Objectives In dermatomyositis (DM), autoantibodies are associated with unique clinical phenotypes. For example, anti-TIF1γ autoantibodies are associated with an increased risk of cancer. The purpose of this study was to discover novel DM autoantibodies. Methods… read more here.
Keywords: tif1 positive; anti sp4; sp4 autoantibodies; anti tif1 ... See more keywords
Dermatomyositis with anti-TIF1-γ antibodies
Sign Up to like & getrecommendations! Published in 2018 at "BMJ Case Reports"
DOI: 10.1136/bcr-2018-227574
Abstract: We report the case of a 61-year-old Turkish male patient who presented to our dermatology outpatient clinic with a 1-year history of swelling and pruritic erythema rash of the face and trunk. He reported associated… read more here.
Keywords: anti tif1; tif1 antibodies; dermatomyositis anti;
Successful treatment of squamous cell carcinoma on the lip with continuous intra-arterial peplomycin infusion chemotherapy: a report of 27 cases
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Dermatology"
DOI: 10.1684/ejd.2022.4235
Abstract: 287 diseases and myositis with mild to moderate symptoms [3]. A large population-based cohort study found that 79.5% of patients with anti-TIF1 antibody-positive DM had developed malignancies within one year after diagnosis, and 8% of… read more here.
Keywords: tif1 antibodies; antibody positive; tif1 antibody; anti tif1 ... See more keywords
Machine Learning Algorithms Identify Clinical Subtypes and Cancer in Anti-TIF1γ+ Myositis: A Longitudinal Study of 87 Patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.802499
Abstract: Background Anti-TIF1γ antibodies are a class of myositis-specific antibodies (MSAs) and are closely associated with adult cancer-associated myositis (CAM). The heterogeneity in anti-TIF1γ+ myositis is poorly explored, and whether anti-TIF1γ+ patients will develop cancer or… read more here.
Keywords: tif1 myositis; anti tif1; cancer; machine learning ... See more keywords
A Commercial Anti-TIF1γ ELISA Is Superior to Line and Dot Blot and Should Be Considered as Part of Routine Myositis-Specific Antibody Testing
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.804037
Abstract: Objectives Anti-TIF1γ is an important autoantibody in the diagnosis of cancer-associated dermatomyositis and the most common autoantibody in juvenile onset dermatomyositis. Its reliable detection is important to instigate further investigations into underlying malignancy in adults.… read more here.
Keywords: tif1; anti tif1; line dot; autoantibody ... See more keywords
Profile of specific and associated autoantibodies in patients with idiopathic inflammatory myopathies in a Colombian population
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.954937
Abstract: Objectives Idiopathic inflammatory myopathies (IIMs) are chronic, autoimmune diseases with several forms of presentation. Diagnosis is mostly clinical in our region. Our aim was to evaluate the autoantibody profile of patients with IIMs. Methods This… read more here.
Keywords: anti ro52; idiopathic inflammatory; specific associated; anti ... See more keywords
First report of anti-TIF1γ dermatomyositis in a patient with myelodysplastic syndrome.
Sign Up to like & getrecommendations! Published in 2017 at "Reumatismo"
DOI: 10.4081/reumatismo.2017.923
Abstract: Inflammatory myopathies as para-neoplastic phenomena were first described by Sterz in 1916. Recently, myositis specific autoantibodies were described in cancer-associated myositis. Anti-transcription intermediary factor 1 gamma (anti-TIF1γ) antibodies have been found in both young adults… read more here.
Keywords: anti tif1; anti; myelodysplastic syndrome; report ... See more keywords
Characteristics of anti-transcriptional intermediary factor 1 gamma autoantibody-positive dermatomyositis patients in Singapore.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Academy of Medicine, Singapore"
DOI: 10.47102/annals-acadmedsg.2022278
Abstract: INTRODUCTION This study aimed to determine the clinical profile and outcome of anti-transcriptional intermediary factor 1 gamma autoantibody (anti-TIF1-γ Ab)-positive dermatomyositis patients and propose cancer screening programmes based on regional cancer trends. METHOD Data on… read more here.
Keywords: tif1 positive; anti transcriptional; positive dermatomyositis; dermatomyositis patients ... See more keywords