Efficacy and Tolerance of Anti–Tumor Necrosis Factor &agr; Agents in Cutaneous Sarcoidosis: A French Study of 46 Cases
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2017.1162
Abstract: Importance Evidence for the long-term efficacy and safety of anti–tumor necrosis factor &agr; agents (anti-TNF) in treating cutaneous sarcoidosis is lacking. Objective To determine the efficacy and safety of anti-TNF in treating cutaneous sarcoidosis in… read more here.
Keywords: cutaneous sarcoidosis; dermatology; anti tnf; sarcoidosis ... See more keywords
Anti-tumour necrosis factor biological therapies for the treatment of uveitic macular oedema (UMO) for non-infectious uveitis.
Sign Up to like & getrecommendations! Published in 2017 at "Cochrane Database of Systematic Reviews"
DOI: 10.1002/14651858.cd012577
Abstract: BACKGROUND Non-infectious uveitis describes a heterogenous group of ocular disorders characterised by intraocular inflammation in the absence of infection. Uveitis is a leading cause of visual loss, most commonly due to uveitic macular oedema (UMO).… read more here.
Keywords: uveitis; anti tnf; treatment; macular oedema ... See more keywords
An Inflammation-Targeting Engineered Probiotic Escherichia coli Nissle 1917 with High Anti-TNF-α Nanobody Secretion Efficacy Alleviates Ulcerative Colitis.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202512360
Abstract: The probiotic Escherichia coli Nissle 1917 (EcN), clinically used for ulcerative colitis (UC) due to its safety and genetic tractability, exhibits limited therapeutic efficacy owing to poor targeting and colonization at inflamed sites. Phosphatidylserine (PS)… read more here.
Keywords: ecn lpp; tnf; efficacy; anti tnf ... See more keywords
A cross‐linked anti‐TNF‐α aptamer for neutralization of TNF‐α‐induced cutaneous Shwartzman phenomenon: A simple and novel approach for improving aptamers' affinity and efficiency
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology Progress"
DOI: 10.1002/btpr.3191
Abstract: To increase the efficiency of aptamers to their targets, a simple and novel method has been developed based on aptamer oligomerization. To this purpose, previously anti‐human TNF‐α aptamer named T1–T4 was trimerized through a trimethyl… read more here.
Keywords: tnf; aptamer; cutaneous shwartzman; anti tnf ... See more keywords
Granulocyte and Monocyte Adsorptive Apheresis Maintenance Therapy Restored the Loss of Response to Anti‐TNF‐Alpha Agents in the Patients With UC: A Case Report
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.70030
Abstract: Ulcerative colitis (UC) is a chronic inflammatory condition requiring lifelong management, with anti‐tumor necrosis factor α (anti‐TNF‐α) agents often used for refractory cases. However, secondary loss of response (LOR) to these agents, due to anti‐drug… read more here.
Keywords: therapy; apheresis; maintenance therapy; anti tnf ... See more keywords
Maintenance-phase serum anti-TNF levels are not associated with mucosal healing in pediatric Crohn's disease.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of pediatric gastroenterology and nutrition"
DOI: 10.1002/jpn3.12471
Abstract: OBJECTIVES Mucosal healing (MH) is a key therapeutic target in Crohn's disease (CD) and is associated with improved outcomes. While adult studies indicate a positive correlation between serum anti-tumor necrosis factor (TNF) levels and MH,… read more here.
Keywords: tnf levels; anti tnf; serum anti; maintenance ... See more keywords
Predictors of antitumor necrosis factor primary nonresponse and drug durability in pediatric inflammatory bowel disease.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of pediatric gastroenterology and nutrition"
DOI: 10.1002/jpn3.70160
Abstract: OBJECTIVES Antitumor necrosis factor (anti-TNF) therapies are first-line therapies for children with inflammatory bowel disease (IBD) (Crohn's disease [CD], ulcerative colitis [UC] and IBD-unclassified [IBD-U]). Limited studies describing anti-TNFs durability and loss of response in… read more here.
Keywords: disease; durability; anti tnf; primary nonresponse ... See more keywords
Gene expression profile predicts response to antitumor necrosis factor in children with Crohn's disease: A Porto group biobank study, and a systematic review.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of pediatric gastroenterology and nutrition"
DOI: 10.1002/jpn3.70197
Abstract: OBJECTIVES There is a paucity of validated predictors of response to anti-tumor necrosis factor (TNF) in pediatric Crohn's disease (CD). We aimed to evaluate the predictive utility of intestinal gene expression to predict response to… read more here.
Keywords: disease; response; anti tnf; expression ... See more keywords
Assessing the possible association of anti‐TNF use with new malignancies: A neglected methodological consideration
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.4579
Abstract: Whether anti‐TNF agents increase, malignancy risk remains debated. The potential problems with comparing the number of observed malignancies in anti‐TNF treated cohorts to number of expected malignancies in national cancer registries could have been an… read more here.
Keywords: tnf; anti tnf; assessing possible; tnf use ... See more keywords
Translation of curative therapy concepts with T cell and cytokine antibody combinations for type 1 diabetes reversal in the IDDM rat
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Medicine"
DOI: 10.1007/s00109-020-01941-8
Abstract: Proinflammatory cytokines released from the pancreatic islet immune cell infiltrate in type 1 diabetes (T1D) cause insulinopenia as a result of severe beta cell loss due to apoptosis. Diabetes prevention strategies targeting different cytokines with… read more here.
Keywords: combination; beta cell; anti tnf; anti tcr ... See more keywords
Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio as predictors of 12-week treatment response and drug persistence of anti-tumor necrosis factor-α agents in patients with rheumatoid arthritis: a retrospective chart review analysis
Sign Up to like & getrecommendations! Published in 2019 at "Rheumatology International"
DOI: 10.1007/s00296-019-04276-x
Abstract: Data are scarce regarding the association of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with treatment response and persistence of anti-TNF-α agents in patients with rheumatoid arthritis (RA). Thus, we investigated whether baseline NLR and… read more here.
Keywords: treatment response; response; anti tnf; agents patients ... See more keywords