Efficacy and Tolerance of Anti–Tumor Necrosis Factor &agr; Agents in Cutaneous Sarcoidosis: A French Study of 46 Cases
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2017.1162
Abstract: Importance Evidence for the long-term efficacy and safety of anti–tumor necrosis factor &agr; agents (anti-TNF) in treating cutaneous sarcoidosis is lacking. Objective To determine the efficacy and safety of anti-TNF in treating cutaneous sarcoidosis in… read more here.
Keywords: cutaneous sarcoidosis; dermatology; anti tnf; sarcoidosis ... See more keywords
Anti-tumour necrosis factor biological therapies for the treatment of uveitic macular oedema (UMO) for non-infectious uveitis.
Sign Up to like & getrecommendations! Published in 2017 at "Cochrane Database of Systematic Reviews"
DOI: 10.1002/14651858.cd012577
Abstract: BACKGROUND Non-infectious uveitis describes a heterogenous group of ocular disorders characterised by intraocular inflammation in the absence of infection. Uveitis is a leading cause of visual loss, most commonly due to uveitic macular oedema (UMO).… read more here.
Keywords: uveitis; anti tnf; treatment; macular oedema ... See more keywords
A cross‐linked anti‐TNF‐α aptamer for neutralization of TNF‐α‐induced cutaneous Shwartzman phenomenon: A simple and novel approach for improving aptamers' affinity and efficiency
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology Progress"
DOI: 10.1002/btpr.3191
Abstract: To increase the efficiency of aptamers to their targets, a simple and novel method has been developed based on aptamer oligomerization. To this purpose, previously anti‐human TNF‐α aptamer named T1–T4 was trimerized through a trimethyl… read more here.
Keywords: tnf; aptamer; cutaneous shwartzman; anti tnf ... See more keywords
Assessing the possible association of anti‐TNF use with new malignancies: A neglected methodological consideration
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.4579
Abstract: Whether anti‐TNF agents increase, malignancy risk remains debated. The potential problems with comparing the number of observed malignancies in anti‐TNF treated cohorts to number of expected malignancies in national cancer registries could have been an… read more here.
Keywords: tnf; anti tnf; assessing possible; tnf use ... See more keywords
Translation of curative therapy concepts with T cell and cytokine antibody combinations for type 1 diabetes reversal in the IDDM rat
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Medicine"
DOI: 10.1007/s00109-020-01941-8
Abstract: Proinflammatory cytokines released from the pancreatic islet immune cell infiltrate in type 1 diabetes (T1D) cause insulinopenia as a result of severe beta cell loss due to apoptosis. Diabetes prevention strategies targeting different cytokines with… read more here.
Keywords: combination; beta cell; anti tnf; anti tcr ... See more keywords
Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio as predictors of 12-week treatment response and drug persistence of anti-tumor necrosis factor-α agents in patients with rheumatoid arthritis: a retrospective chart review analysis
Sign Up to like & getrecommendations! Published in 2019 at "Rheumatology International"
DOI: 10.1007/s00296-019-04276-x
Abstract: Data are scarce regarding the association of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with treatment response and persistence of anti-TNF-α agents in patients with rheumatoid arthritis (RA). Thus, we investigated whether baseline NLR and… read more here.
Keywords: treatment response; response; anti tnf; agents patients ... See more keywords
Pregnancy outcomes in partners of male ankylosing spondylitis patients treated with anti-tumour necrosis factor-α biologics: real-life results from a single-centre cross-sectional study
Sign Up to like & getrecommendations! Published in 2020 at "Rheumatology International"
DOI: 10.1007/s00296-020-04518-3
Abstract: Most patients with inflammatory arthritis are at their reproductive ages. Use of anti-tumour necrosis factor alpha (anti-TNF-α) agents, one of the important treatment options for inflammatory arthritis, can cause foetal morbidity and mortality. While most… read more here.
Keywords: outcomes partners; pregnancy; tnf agents; anti tnf ... See more keywords
Reply to: Comment on “effects of 1-year anti-TNF-α therapy on vascular function in rheumatoid arthritis and ankylosing spondylitis” by Cure et al.
Sign Up to like & getrecommendations! Published in 2020 at "Rheumatology International"
DOI: 10.1007/s00296-020-04521-8
Abstract: We thank Dr. Cure and Dr. Cure for their helpful comments. Authors list some studies that show numerical progression of cIMT over time despite biologic treatment [2–4]. They also refer to our paper [1]. However,… read more here.
Keywords: control group; cimt; anti tnf; reply comment ... See more keywords
Postoperative course of laparoscopic subtotal colectomy is affected by prolonged preoperative anti-TNF therapy in patients with acute colitis complicating inflammatory bowel disease
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Colorectal Disease"
DOI: 10.1007/s00384-017-2850-4
Abstract: PurposeThe aim of medical treatment of severe acute colitis (SAC) complicating inflammatory bowel disease (IBD) is to avoid surgery, but in 20 to 50% of the cases, colectomy remains necessary. This study aimed to determine… read more here.
Keywords: laparoscopic subtotal; subtotal colectomy; anti tnf; postoperative course ... See more keywords
Enterocutaneous fistula in severely active Crohn’s disease: preoperative anti-TNF alpha treatment to limit bowel resection—report of a case
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Colorectal Disease"
DOI: 10.1007/s00384-018-3206-4
Abstract: PurposeStrategies for limiting the extent of bowel resection in cases of enterocutaneous or interenteric fistulas in severely active Crohn’s disease are urgently necessary. Anti-inflammatory therapy with tumor necrosis factor alpha (anti-TNF alpha) inhibitors has positive… read more here.
Keywords: bowel resection; tnf alpha; disease; anti tnf ... See more keywords
Effect of antinuclear antibodies on pharmacokinetics of anti-TNF therapy in patients with inflammatory bowel disease
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Colorectal Disease"
DOI: 10.1007/s00384-021-04091-6
Abstract: The detection of antinuclear antibodies (ANA) in serum of patients with inflammatory bowel disease (IBD) has been associated with a worse response to anti-TNF therapy and the development of cutaneous or arthritic manifestations. The aim… read more here.
Keywords: anti tnf; therapy; ana positivity; disease ... See more keywords