Reprogramming immunosuppressive myeloid cells by activated T cells promotes the response to anti-PD-1 therapy in colorectal cancer
Sign Up to like & getrecommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-020-00377-3
Abstract: Overcoming local immunosuppression is critical for immunotherapy to produce robust anti-tumor responses. Myeloid-derived suppressor cells (MDSCs) are key regulators of immunosuppressive networks and promote tumor progression. However, it remains unclear whether and how tumor-infiltrating MDSCs… read more here.
Keywords: response; anti treatment; activated cells; therapy ... See more keywords
Anti-interleukin-1 treatment in 26 patients with refractory familial mediterranean fever
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DOI: 10.1080/14397595.2016.1194510
Abstract: Abstract Objective: To investigate the effect of anti-interleukin-1 (anti-IL-1) treatment on the frequency and severity of attacks and other disease-related clinical parameters and to evaluate the adverse effects associated with anti-IL-1 treatment in 26 patients… read more here.
Keywords: anti treatment; treatment; treatment patients; colchicine ... See more keywords
The Role of Anti-IL-1 Treatment in MIS-C Patients
Sign Up to like & getrecommendations! Published in 2021 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2022.2006631
Abstract: Since the beginning of the COVID-19 pandemic with the first cases reported in December 2019 in the city of Wuhan, it was clear that the pediatric population had low susceptibility to SARS CoV-2 infection as… read more here.
Keywords: anti treatment; syndrome; sars cov; role anti ... See more keywords
High efavirenz serum concentrations in TB/HIV-coinfected Ugandan adults with a CYP2B6 516 TT genotype on anti-TB treatment
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dky379
Abstract: Objectives To report the efavirenz serum concentrations in TB/HIV-coinfected Ugandan adults on concomitant anti-TB treatment and analyse factors associated with elevated concentrations in this specific population. Methods Serum efavirenz concentrations in TB/HIV-coinfected Ugandan adults on… read more here.
Keywords: cyp2b6 516; efavirenz serum; anti treatment; serum concentrations ... See more keywords
Clinical significance of BIM deletion polymorphism in chemoradiotherapy for non‐small cell lung cancer
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DOI: 10.1111/cas.14711
Abstract: The standard treatment for locally advanced non‐small cell lung cancer (NSCLC) is chemoradiotherapy (CRT) followed by anti‐programmed cell death‐ligand 1 (anti‐PD‐L1) treatment. BIM deletion polymorphism induces the suppression of apoptosis resulting from epidermal growth factor… read more here.
Keywords: bim polymorphism; anti treatment; bim deletion; treatment ... See more keywords
The effect of anti‐IL‐17 treatment on the reaction to a nickel patch test in patients with allergic contact dermatitis
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Dermatology"
DOI: 10.1111/ijd.14347
Abstract: predominance in Asians. Recent studies have identified mutations in the genes encoding for c-Secretase protein and its subunits in patients with HS. A study of 53 Chinese patients with familial HS and confirmed nicastrin mutations… read more here.
Keywords: reaction nickel; effect anti; anti treatment; patch test ... See more keywords
Gut Mycobiota Dysbiosis in Pulmonary Tuberculosis Patients Undergoing Anti-Tuberculosis Treatment
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DOI: 10.1128/spectrum.00615-21
Abstract: Numerous studies have shown that the gut bacterial microbiota is altered in active TB patients and that anti-TB drugs have profound and long-term impacts. However, as an integral part of the microbiota, fungi have rarely… read more here.
Keywords: anti treatment; dysbiosis; tuberculosis; treatment ... See more keywords
CAMK1D Triggers Immune Resistance of Human Tumor Cells Refractory to Anti–PD-L1 Treatment
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology Research"
DOI: 10.1158/2326-6066.cir-19-0608
Abstract: Genetic screens identify the kinase CAMK1D as a regulator of antitumor immune resistance in anti–PD-L1–refractory cancer. CAMK1D activation in tumor cells, through CTL stimulation of the Fas receptor, inhibits caspase-mediated cell death of anti–PD-L1–refractory tumors.… read more here.
Keywords: immune resistance; resistance; camk1d; tumor ... See more keywords
Level of and associated factors for non-adherence to anti-tuberculosis treatment among tuberculosis patients in Gamo Gofa zone, southern Ethiopia: cross-sectional study
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DOI: 10.1186/s12889-020-09827-7
Abstract: Non-adherence to anti-TB treatment is one of the crucial challenges in improving tuberculosis (TB) treatment outcomes and reducing healthcare costs. The poor adherence to anti-TB treatment among patients with TB is a major problem in… read more here.
Keywords: adherence anti; anti treatment; treatment; tuberculosis ... See more keywords
Could We Predict the Response of Immune Checkpoint Inhibitor Treatment in Hepatocellular Carcinoma?
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DOI: 10.3390/cancers14133213
Abstract: Simple Summary The use of anti-programmed cell-death protein (ligand)-1 (PD-[L]1) is now a standard of care for treating hepatocellular carcinoma (HCC). However, the treatment only benefits 10–20% of patients when used as a monotherapy. The… read more here.
Keywords: hepatocellular carcinoma; anti treatment; hcc; treatment ... See more keywords
Coordinated In Vitro Release of Granulysin, Perforin and IFN-γ in TB and HIV/TB Co-Infection Associated with Clinical Outcomes before and after Anti-TB Treatment
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DOI: 10.3390/pathogens9080655
Abstract: Granule-associated killing molecules released from cytotoxic T lymphocytes participate as a crucial step in immunity against tuberculosis (TB), but the role of coordinated production remains controversial. Coordinated release of effector molecules in vitro after stimulating… read more here.
Keywords: anti treatment; hiv; ifn; perforin ... See more keywords