In vitro anti-Trypanosoma cruzi evaluation of sesquiterpenes from the branches of Oxandra sessiliflora
Sign Up to like & getrecommendations! Published in 2020 at "Phytochemistry Letters"
DOI: 10.1016/j.phytol.2020.04.005
Abstract: Abstract In this work, the CH2Cl2 phase from the EtOH extract of Oxandra sessiliflora (Annonaceae) branches was subjected to chromatographic fractionation to afford six sesquiterpenoids: 4α,10β-aromadendranediol (1), 4β,10α-aromadendranediol (2), 4α,10α-aromadendranediol (3), 1β,6α-dihydroxy-4(15)-eudesmene (4), 4β,10α-dihydroxy-guai-6-ene (5),… read more here.
Keywords: anti trypanosoma; vitro anti; cruzi evaluation; oxandra sessiliflora ... See more keywords
Antileshimania, anti-Trypanosoma cruzi and antimicrobial activities of scandenin and 4'-O-methylderrone from Deguelia costata.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2140336
Abstract: Scandenin and 4'-O-methylderrone were isolated from the ethanol extract of the roots and dichloromethane extract of the leaves of Deguelia costata (Benth.) A.M.G. Azevedo & R.A. Camargo, respectively. These compounds and their extracts had their… read more here.
Keywords: scandenin methylderrone; antileshimania anti; methylderrone; anti trypanosoma ... See more keywords
Identification of Anti-Trypanosoma cruzi Lead Compounds with Putative Immunomodulatory Activity
Sign Up to like & getrecommendations! Published in 2018 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01834-17
Abstract: ABSTRACT In seeking substitutions for the current Chagas disease treatment, which has several relevant side effects, new therapeutic candidates have been extensively investigated. In this context, a balanced interaction between mediators of the host immune… read more here.
Keywords: proinflammatory; pyr; cd8; anti trypanosoma ... See more keywords
Anti-Trypanosoma cruzi Properties of Sesquiterpene Lactones Isolated from Stevia spp.: In Vitro and In Silico Studies
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15020647
Abstract: Stevia species (Asteraceae) have been a rich source of terpenoid compounds, mainly sesquiterpene lactones, several of which show antiprotozoal activity. In the search for new trypanocidal compounds, S. satureiifolia var. satureiifolia and S. alpina were… read more here.
Keywords: anti trypanosoma; sesquiterpene lactones; trypanosoma cruzi; properties sesquiterpene ... See more keywords