Remotely Guided Immunobots Engaged in Anti-Tumorigenic Phenotypes for Targeted Cancer Immunotherapy.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202204016
Abstract: Building medical microrobots from the body's own cells may circumvent the biocompatibility concern and hence presents more potential in clinical applications to improve the possibility of escaping from the host defense mechanism. More importantly, live… read more here.
Keywords: immunobots engaged; guided immunobots; tumorigenic phenotypes; anti tumorigenic ... See more keywords
Deguelin, a Novel Anti-Tumorigenic Agent in Human Esophageal Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2017.11.010
Abstract: Article history: Received 15 November 2017 Accepted 15 November 2017 Available online 16 November 2017 example targeting Raf-1, Bcr, and Cdc25 phosphatase. Deguelin has the potential to impair 14-3-3 protein function through inhibition of Aurora… read more here.
Keywords: november 2017; tumorigenic agent; anti tumorigenic; novel anti ... See more keywords
The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-74368-3
Abstract: The pancreatic tumour stroma is composed of phenotypically heterogenous cancer-associated fibroblasts (CAFs) with both pro- and anti-tumorigenic functions. Here, we studied the impact of calcipotriol, a vitamin D3 analogue, on the activation of human pancreatic… read more here.
Keywords: cafs; anti tumorigenic; human pancreatic; vitamin analogue ... See more keywords
Abstract 5171: TP-6379, an investigational TGFBR1 inhibitor, shown to remodel the tumor microenvironment and enhance anti-tumorigenic immunological responses in syngeneic mouse models of cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-5171
Abstract: Transforming growth factor-β (TGF-β) receptors regulate SMAD signal transduction and a wide-range of biological processes including, wound healing, angiogenesis, immune modulation, epithelial-mesenchymal transition, cell differentiation, apoptosis, growth, and motility. In transformed cells, TGF-β signaling is… read more here.
Keywords: mouse; anti tumorigenic; treatment; tumor ... See more keywords
The anti-tumorigenic activity of A2M—A lesson from the naked mole-rat
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DOI: 10.1371/journal.pone.0189514
Abstract: Cancer resistance is a major cause for longevity of the naked mole-rat. Recent liver transcriptome analysis in this animal compared to wild-derived mice revealed higher expression of alpha2-macroglobulin (A2M) and cell adhesion molecules, which contribute… read more here.
Keywords: tumorigenic activity; anti tumorigenic; mole rat; naked mole ... See more keywords
Decipering the Molecular Mechanism of ACE2 Regulating A549 Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.653725
Abstract: Angiotensin-converting enzyme 2 (ACE2) is an aminopeptidase that functions as a part of the renin-angiotensin system (RAS). The RAS pathway plays a crucial role in regulating the local blood flow within a tissue. As a… read more here.
Keywords: anti tumorigenic; mechanism ace2; molecular mechanism; cancer cells ... See more keywords
Asparagus officinalis Exhibits Anti-Tumorigenic and Anti-Metastatic Effects in Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.688461
Abstract: Ovarian cancer is one of the leading causes of female cancer death. Emerging evidence suggests that many dietary natural products have anti-tumorigenic activity, including that of asparagus officinalis. The current study aimed to assess the… read more here.
Keywords: anti tumorigenic; asparagus officinalis; tumorigenic anti; ovarian cancer ... See more keywords
Anti-tumorigenic and Platinum-Sensitizing Effects of Apolipoprotein A1 and Apolipoprotein A1 Mimetic Peptides in Ovarian Cancer
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DOI: 10.3389/fphar.2018.01524
Abstract: Objective: Apolipoprotein A1 (ApoA1) is remarkably decreased in serum and ovarian tissues of ovarian cancer patients. ApoA1 and ApoA1 mimetic peptides can sequestrate pro-inflammatory phospholipids, some of which are known to activate a variety of… read more here.
Keywords: mimetic peptides; anti tumorigenic; ovarian cancer; mimetic peptide ... See more keywords
Cannabinoid compounds in combination with curcumin and piperine display an anti-tumorigenic effect against colon cancer cells
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1145666
Abstract: Currently, use of cannabinoids is limited to improve adverse effects of chemotherapy and their palliative administration during treatment is curiously concomitant with improved prognosis and regressed progression in patients with different tumor types. Although, non-psychoactive… read more here.
Keywords: cell; display; combination; curcumin piperine ... See more keywords
Anti-Tumorigenic and Anti-Metastatic Activity of the Sponge-Derived Marine Drugs Aeroplysinin-1 and Isofistularin-3 against Pheochromocytoma In Vitro
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DOI: 10.3390/md16050172
Abstract: Over 10% of pheochromocytoma and paraganglioma (PPGL) patients have malignant disease at their first presentation in the clinic. Development of malignancy and the underlying molecular pathways in PPGLs are poorly understood and efficient treatment strategies… read more here.
Keywords: pheochromocytoma; anti tumorigenic; tumorigenic anti; isofistularin ... See more keywords