Antiapoptotic and anti‐inflammatory effects of Pparγ agonist, pioglitazone, reversed Dox‐induced cardiotoxicity through mediating of miR‐130a downregulation in C57BL/6 mice
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DOI: 10.1002/jbt.23041
Abstract: Doxorubicin (Dox) is an antitumor agent widely used in cancer therapy, with notable side effects of cardiac toxicity. Peroxisome proliferator‐activated receptor γ (PPARγ), is a transcriptional factor with antiapoptotic and anti‐inflammatory properties. Recently we indicated… read more here.
Keywords: ppar; mir 130a; dox; dox induced ... See more keywords