Safety and Interactions of Direct Oral Anticoagulants with Antiarrhythmic Drugs
Sign Up to like & getrecommendations! Published in 2017 at "Drug Safety"
DOI: 10.1007/s40264-017-0567-5
Abstract: Direct oral anticoagulants (DOACs) are novel direct-acting medications that are selective for either thrombin or activated factor X. Due to their obvious benefits for patients (fewer interactions, broader therapeutic window, etc.), they are increasingly used… read more here.
Keywords: safety interactions; oral anticoagulants; safety; direct oral ... See more keywords
Nano-scale drug delivery systems for antiarrhythmic agents.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.08.080
Abstract: Arrhythmia means the heart is beating too fast, too slow, or with an irregular pattern. Due to the side effects and low bioavailability of many antiarrhythmic drugs, nano-encapsulation has been widely used for their targeted… read more here.
Keywords: antiarrhythmic agents; drug delivery; delivery; delivery systems ... See more keywords
Inhibition of cardiac Kv4.3 (Ito) channel isoforms by class I antiarrhythmic drugs lidocaine and mexiletine.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173159
Abstract: Transient outward K+ current, Ito, contributes to cardiac action potential generation and is primarily carried by Kv4.3 (KCND3) channels. Two Kv4.3 isoforms are expressed in human ventricle and show differential remodeling in heart failure (HF).… read more here.
Keywords: lidocaine mexiletine; kv4 isoforms; mexiletine; antiarrhythmic drugs ... See more keywords
Does antiarrhythmic drugs premedication improve electrical cardioversion success in persistent atrial fibrillation?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of electrocardiology"
DOI: 10.1016/j.jelectrocard.2016.12.004
Abstract: AIMS Aim of this study is to evaluate the impact of antiarrhythmic drugs (AADs) administration for at least one month before ECV on the acute and long term success rate of the procedure. METHODS 1313… read more here.
Keywords: long term; group; success; log rank ... See more keywords
Maastricht antiarrhythmic drug evaluator (MANTA): a computational tool for better understanding of antiarrhythmic drugs.
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacological research"
DOI: 10.1016/j.phrs.2019.104444
Abstract: Cardiac arrhythmias are a global health burden, contributing significantly to morbidity and mortality worldwide. Despite technological advances in catheter ablation therapy, antiarrhythmic drugs (AADs) remain a cornerstone for the management of cardiac arrhythmias. Experimental and… read more here.
Keywords: class; tool; drug; better understanding ... See more keywords
RIVAROXABAN IN COMBINATION WITH ANTIARRHYTHMIC DRUGS DOES NOT INCREASE THE BLEEDING RISKS IN PATIENTS WITH NON-PERMANENT ATRIAL FIBRILLATION
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(20)30957-8
Abstract: Rivaroxaban (RIVA) is useful for stroke prevention in atrial fibrillation (AF) patients. Antiarrhythmic drugs (AADs) prevent the recurrence of AF in non-permanent AF (npAF). There are limited data regarding drug-drug interactions between RIVA and AADs.… read more here.
Keywords: atrial fibrillation; non permanent; combination antiarrhythmic; rivaroxaban combination ... See more keywords
Antiarrhythmic drugs in patients with early persistent atrial fibrillation and heart failure: results of the RACE 3 study
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DOI: 10.1093/europace/euab062
Abstract: Abstract Aims Maintaining sinus rhythm in patients with persistent atrial fibrillation (AF) is challenging. We explored the efficacy of class I and III antiarrhythmic drugs (AADs) in patients with persistent AF and mild to moderate… read more here.
Keywords: atrial fibrillation; patients early; persistent atrial; sinus rhythm ... See more keywords
Cardiovascular outcomes in patients with atrial fibrillation concomitantly treated with antiarrhythmic drugs and non-vitamin k antagonist oral anticoagulants
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DOI: 10.1093/europace/euad083
Abstract: Abstract Aims Limited data compared antiarrhythmic drugs (AADs) with concomitant non-vitamin K antagonist oral anticoagulants in atrial fibrillation patients, hence the aim of the study. Methods and results National health insurance database were retrieved during… read more here.
Keywords: vitamin antagonist; non vitamin; dronedarone; antagonist oral ... See more keywords
Efficacy and safety of ShenSongYangXin Capsule combined with antiarrhythmic drugs for atrial fibrillation
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DOI: 10.1097/md.0000000000022367
Abstract: Abstract Background: Shen-Song-Yang-Xin Capsule (SSYX), a Chinese patent medicine, combined with antiarrhythmic drugs (AADs) in the treatment of atrial fibrillation (AF) has been widely applied in clinical practice, but the results are controversial. This study… read more here.
Keywords: efficacy safety; medicine; efficacy; atrial fibrillation ... See more keywords
Class 1C antiarrhythmic drugs in atrial fibrillation and coronary artery disease
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DOI: 10.1111/jce.14335
Abstract: Class 1C antiarrhythmic drugs (AADs) are effective first‐line agents for atrial fibrillation (AF) treatment. However, these agents commonly are avoided in patients with known coronary artery disease (CAD), due to known increased risk in the… read more here.
Keywords: atrial fibrillation; class antiarrhythmic; coronary artery; antiarrhythmic drugs ... See more keywords
Electrocardiographic marker of the cardiac action potential triangulation induced by antiarrhythmic drugs in perfused guinea‐pig heart
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DOI: 10.1113/ep090349
Abstract: What is the central question of this study? Can the triangular appearance of ventricular action potential, indicating proarrhythmic profile of antiarrhythmic agent, be approximated by specific changes on an electrocardiogram (ECG)? What are the main… read more here.
Keywords: triangulation; electrocardiographic marker; action potential; action ... See more keywords