Antiarrhythmic effects of dantrolene in human diseased cardiomyocytes.
Sign Up to like & getrecommendations! Published in 2017 at "Heart rhythm"
DOI: 10.1016/j.hrthm.2016.09.014
Abstract: BACKGROUND Cardiac type 2 ryanodine receptors (RyR2s) play a pivotal role in cellular electrophysiology and contractility. Increased RyR2-mediated diastolic sarcoplasmic reticulum (SR) Ca2+ release is linked to heart failure (HF) and arrhythmias. Dantrolene, a drug… read more here.
Keywords: antiarrhythmic effects; dantrolene human; diseased cardiomyocytes; ca2 ... See more keywords
Anticoagulant and antiarrhythmic effects of heparin in the treatment of COVID‐19 patients
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.14902
Abstract: Abstract Most severe manifestations of COVID‐19 cases, such as multiple organ failure and death, have been linked to coagulation dysfunction markers, such as platelet reduction and increases in prothrombin time, fibrin degradation products and, mainly,… read more here.
Keywords: antiarrhythmic effects; covid patients; anticoagulant antiarrhythmic; heparin treatment ... See more keywords
CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2
Sign Up to like & getrecommendations! Published in 2023 at "Circulation Research"
DOI: 10.1161/circresaha.122.322031
Abstract: Background: Ventricular arrhythmia and sudden cardiac death are the most common lethal complications after myocardial infarction. Antiarrhythmic pharmacotherapy remains a clinical challenge and novel concepts are highly desired. Here, we focus on the cardioprotective CNP… read more here.
Keywords: cnp; promotes antiarrhythmic; effects via; cnp promotes ... See more keywords