Polymyxin B-Polysaccharide Polyion Nanocomplex with Improved Biocompatibility and Unaffected Antibacterial Activity for Acute Lung Infection Management.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201901542
Abstract: The decade-old antibiotic, polymyxin B (PMB), is regarded as the last line defense against gram-negative "superbug." However, the serious nephrotoxicity and neurotoxicity strongly obstruct further application of this highly effective antibiotic. Herein, a charge switchable… read more here.
Keywords: antibacterial activity; pmb; polyion nanocomplex; acute lung ... See more keywords
Ultrasound‐Enhanced Antibacterial Activity of Polymeric Nanoparticles for Eradicating Bacterial Biofilms
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DOI: 10.1002/adhm.202201060
Abstract: Bacterial biofilms are a major healthcare concern resulting in refractory conditions such as chronic wounds, implant infections and failure, and multidrug‐resistant infections. Aggressive and invasive strategies are employed to cure biofilm infections but are prone… read more here.
Keywords: ultrasound enhanced; antibacterial activity; bacterial biofilms; polymeric nanoparticles ... See more keywords
Mn Single‐Atom Nanozyme Functionalized 3D‐Printed Bioceramic Scaffolds for Enhanced Antibacterial Activity and Bone Regeneration
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202303182
Abstract: Infective bone defect is increasingly threatening human health. How to achieve the optimal antibacterial activity and regenerative repair of infective bone defect simultaneously is a huge challenge in clinic. Herein, this work reports a rational… read more here.
Keywords: hsae bcp; antibacterial activity; enhanced antibacterial; bone regeneration ... See more keywords
A Bacterial Cellulose Nanocrystals‐Graphene Oxide/ Poly(Vinyl Alcohol) @Vanillin Composite Fibers with Efficient Antibacterial Activity and High Strength for Surgical Suturing
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DOI: 10.1002/adhm.202404511
Abstract: Antibacterial activity is one of the indispensable properties of functional sutures. However, traditional strategies for developing antibacterial sutures inevitably compromise the inherent mechanical strength of the fibers. Developing advanced sutures with balanced antibacterial and mechanical… read more here.
Keywords: cellulose nanocrystals; graphene oxide; bacterial cellulose; antibacterial activity ... See more keywords
An Injectable Hydrogel with Ultrahigh Burst Pressure and Innate Antibacterial Activity for Emergency Hemostasis and Wound Repair
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Materials"
DOI: 10.1002/adma.202404811
Abstract: Uncontrolled bleeding and wound infections following severe trauma pose significant challenges for existing tissue adhesives, primarily due to their weak wet adhesion, slow adhesion formation, cytotoxicity concerns, and lack of antibacterial properties. Herein, an injectable… read more here.
Keywords: burst pressure; injectable hydrogel; antibacterial activity; repair ... See more keywords
Cinchonidinyl‐Based Acrylic and Methacrylic Homopolymers: Synthesis, Characterization, and Antibacterial Activity
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DOI: 10.1002/adv.21572
Abstract: The monomers (5-ethenyl-1-azabicyclo [2.2.2] octan-2-yl)-quinolin-4-ylmethyl acrylate (EAOQMA) and (5-ethenyl-1-azabicyclo [2.2.2] octan-2-yl)-quinolin-4-ylmethyl methacrylate (EAOQMMA) were synthesized by reacting (5-ethenyl-1-azabicyclo octan-2-yl)-quinolin-4-ylmethanol [cinchonidine] with acryloylchloride and methacryloyl chloride, respectively, in the presence of triethylamine. The homopolymers were synthesized… read more here.
Keywords: cinchonidinyl based; antibacterial activity; azabicyclo octan; octan quinolin ... See more keywords
Versatile Hydrogel Dressing with Skin Adaptiveness and Mild Photothermal Antibacterial Activity for Methicillin‐Resistant Staphylococcus Aureus‐Infected Dynamic Wound Healing
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DOI: 10.1002/advs.202206585
Abstract: Bacterial infection often induces chronic repair of wound healing owing to aggravated inflammation. Hydrogel dressing exhibiting intrinsic antibacterial activity may substantially reduce the use of antibiotics for infected wound management. Hence, a versatile hydrogel dressing… read more here.
Keywords: antibacterial activity; wound healing; hydrogel; hydrogel dressing ... See more keywords
Synthesis, X‐ray, Hirshfeld Surface Analysis, Antibacterial Activity, and Computational Investigations of New Benzimidazo[1,2‐c]quinazolines and Indolo[2,3‐b]quinoxalines
Sign Up to like & getrecommendations! Published in 2025 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.70222
Abstract: Novel benzimidazo[1,2‐c]quinazoline and indolo[2,3‐b]quinoxaline derivatives were synthesized and characterized using 1H and 13C NMR, LC‐MS, and single‐crystal X‐ray diffraction techniques. A detailed analysis of the surface properties, intermolecular interactions, crystal packing characteristics, and antibacterial activity… read more here.
Keywords: antibacterial activity; analysis; ray; hirshfeld surface ... See more keywords
Synthesis, characterization, density functional theory studies and antibacterial activity of a new Schiff base dioxomolybdenum(VI) complex with tryptophan as epoxidation catalyst
Sign Up to like & getrecommendations! Published in 2017 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.3782
Abstract: Appl Organometal Chem. 2017;e3782. https://doi.org/10.1002/aoc.3782 A cis‐dioxomolybdenum(VI) complex was prepared with MoO2(acac)2 and a Schiff base ligand (2‐((2‐hydroxybenzylidene)amino)‐3‐(1H‐indol‐3‐yl)propanoic acid) derived from salicylaldehyde and L‐tryptophan in ethanol and designated as [MoO2(Sal‐Tryp)(EtOH)]. It was characterized using several… read more here.
Keywords: density functional; antibacterial activity; functional theory; dioxomolybdenum complex ... See more keywords
Comparison of prolonged antibacterial activity and release profile of propolis‐incorporated PVA nanofibrous mat, microfibrous mat, and film
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DOI: 10.1002/app.45794
Abstract: Propolis as a natural antibacterial agent was incorporated into the poly(vinyl alcohol) (PVA) in different forms of nanofiber, microfiber, and film. The successful fabrication of uniform nanofibers with 85–314 nm diameters and microfibers with 2.02… read more here.
Keywords: nanofibrous mat; mat film; antibacterial activity; film ... See more keywords
Semi‐synthesis, antibacterial activity, and molecular docking study of novel pleuromutilin derivatives bearing cinnamic acids moieties
Sign Up to like & getrecommendations! Published in 2019 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.201800266
Abstract: To develop new antibiotics owning a special mechanism, we used the molecular assembly method to synthesize a series of novel pleuromutilin derivatives containing a cinnamic acid scaffold at the C‐14 side chain. We evaluated their… read more here.
Keywords: study; antibacterial activity; pleuromutilin derivatives; activity ... See more keywords