Reaching toward underexplored targets in antibacterial drug design
Sign Up to like & getrecommendations! Published in 2019 at "Drug Development Research"
DOI: 10.1002/ddr.21465
Abstract: The increase of antimicrobial resistance necessitates the renewal and strong research involvement in antibacterial drug design. In the following work, we comment on the key approaches used in development of new antibacterials, focusing on intracellular… read more here.
Keywords: research; antibacterial drug; drug design; drug ... See more keywords
Japanese Antibacterial Drug Management for Cardiac Sarcoidosis (J‐ACNES): A multicenter, open‐label, randomized, controlled study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Arrhythmia"
DOI: 10.1002/joa3.12084
Abstract: Cardiac sarcoidosis (CS) is a noncaseating granulomatous disease of unknown etiology. Lifelong immunosuppressive therapy, most frequently using corticosteroids, is a standard therapy to control hypersensitivity of immune reactions and prevent inflammation. However, it sometimes causes… read more here.
Keywords: japanese antibacterial; therapy; drug management; antibacterial drug ... See more keywords
Effects of Multicide, Antibacterial Drug, on Staphylococcus Biomembranes
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-017-3902-z
Abstract: Drug penetration into bacterial biomembranes is one of the most important factors determining the efficiency of antibacterial therapy. Multicide, antibacterial drug, is a nanomolecule 1.3-2.0 nm in size, easily penetrating into staphylococcus biomembranes and causing… read more here.
Keywords: effects multicide; staphylococcus biomembranes; antibacterial drug; drug ... See more keywords
Fabrication of functionalized carbon nanofibers/carbon black composite for electrochemical investigation of antibacterial drug nitrofurantoin
Sign Up to like & getrecommendations! Published in 2021 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2021.127112
Abstract: Abstract The derivative of nitro groups containing antibacterial drug is very essential in present days for the urinary infections of human beings and animals, therefore, monitoring or controlling the usage of these drugs are more… read more here.
Keywords: drug; functionalized carbon; antibacterial drug; cnf ... See more keywords
Benzothiazole-based Compounds in Antibacterial Drug Discovery.
Sign Up to like & getrecommendations! Published in 2018 at "Current medicinal chemistry"
DOI: 10.2174/0929867324666171009103327
Abstract: Numerous compounds with a benzothiazole scaffold that have been described in the literature show promising activities against several Gram-positive and Gramnegative bacteria, and also against Mycobacterium tuberculosis. Benzothiazole-based antibacterial compounds bind to different biological targets… read more here.
Keywords: bacterial cells; benzothiazole; antibacterial drug; benzothiazole based ... See more keywords
Machine Learning in Antibacterial Drug Design
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.864412
Abstract: Advances in computer hardware and the availability of high-performance supercomputing platforms and parallel computing, along with artificial intelligence methods are successfully complementing traditional approaches in medicinal chemistry. In particular, machine learning is gaining importance with… read more here.
Keywords: machine; machine learning; antibacterial agents; antibacterial drug ... See more keywords
Bioinformatics and Genomic Analyses of the Suitability of Eight Riboswitches for Antibacterial Drug Targets
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11091177
Abstract: Antibiotic resistance (AR) is an acute problem that results in prolonged and debilitating illnesses. AR mortality worldwide is growing and causes a pressing need to research novel mechanisms of action and untested target molecules. This… read more here.
Keywords: eight riboswitches; riboswitches antibacterial; antibacterial drug; suitability ... See more keywords
Antibacterial Drug-Release Polydimethylsiloxane Coating for 3D-Printing Dental Polymer: Surface Alterations and Antimicrobial Effects
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceuticals"
DOI: 10.3390/ph13100304
Abstract: Polymers are the most commonly used material for three-dimensional (3D) printing in dentistry; however, the high porosity and water absorptiveness of the material adversely influence biofilm formation on the surface of the 3D-printed dental prostheses.… read more here.
Keywords: antibacterial drug; surface; polymer; printing dental ... See more keywords