Costs are a major driver of antibacterial drug prescriptions in Germany: market analysis from 1985 to 2022
Sign Up to like & getrecommendations! Published in 2024 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-024-03171-y
Abstract: In recent years, several threatening developments regarding antibacterial drugs, such as rising bacterial resistance and delivery bottlenecks, have occurred. Since antibacterial drugs are crucial for modern medicine, understanding events and influencing factors relevant for long-term… read more here.
Keywords: 1985 2022; major driver; antibacterial drugs; drug ... See more keywords
Current Landscape and Future Perspective of Oxazolidinone Scaffolds Containing Antibacterial Drugs.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c00480
Abstract: The widespread use of antibiotics has made the problem of bacterial resistance increasingly serious, and the study of new drug-resistant bacteria has become the main direction of antibacterial drug research. Among antibiotics, the fully synthetic… read more here.
Keywords: antibacterial drugs; landscape future; oxazolidinone antibacterial; future perspective ... See more keywords
Simultaneous oxidative determination of antibacterial drugs in aqueous solutions using an electrode modified with MWCNTs decorated with Fe3O4 nanoparticles
Sign Up to like & getrecommendations! Published in 2018 at "New Journal of Chemistry"
DOI: 10.1039/c8nj00129d
Abstract: The present study describes a simple sensor developed from Fe3O4 and MWCNT nanoparticles for the simultaneous detection of sulfamethoxazole (SMX) and trimethoprim (TMP). Determination was carried out using cyclic voltammetry, electrochemical impedance spectroscopy, chronoamperometry and… read more here.
Keywords: determination antibacterial; nanoparticles simultaneous; antibacterial drugs; determination ... See more keywords
Antibacterial drugs and cyclodextrin inclusion complexes: a patent review
Sign Up to like & getrecommendations! Published in 2023 at "Expert Opinion on Drug Delivery"
DOI: 10.1080/17425247.2023.2175815
Abstract: ABSTRACT Introduction Bacterial antibiotic resistance occurs when bacteria mutate and escape the effect of antibiotics, which makes the antibiotics no longer effective in treating infections. New solutions for bacterial infections are a persistent need including… read more here.
Keywords: review; patent; antibacterial drugs; inclusion complexes ... See more keywords
Clinical efficacy of antibacterial drugs combined with Proton Pump Inhibitors and Bismuth in the treatment of Helicobacter Pylori-infected Peptic Ulcer
Sign Up to like & getrecommendations! Published in 2025 at "Pakistan Journal of Medical Sciences"
DOI: 10.12669/pjms.41.11.12314
Abstract: ABSTRACT Objective: To investigate the clinical efficacy of antibacterial drugs combined with proton pump inhibitors and bismuth in the treatment of Helicobacter pylori (Hp)-infected peptic ulcer. Methodology: This was a retrospective study. A total of… read more here.
Keywords: treatment; proton pump; control group; group ... See more keywords
Effect of 2-chloro-N-(4-fluoro-3-nitrophenyl)acetamide in combination with antibacterial drugs against Klebsiella pneumoniae.
Sign Up to like & getrecommendations! Published in 2023 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765202320210141
Abstract: Klebsiella pneumoniae is a species of Gram-negative bacteria related to a wide range of infections and high rates of drug resistance. The combined use of antibacterial agents is one of the strategies that has been… read more here.
Keywords: fluoro nitrophenyl; pneumoniae; antibacterial drugs; chloro fluoro ... See more keywords
Lean Six Sigma as a Management Tool Helps Standardize Antimicrobial Use in Hospital Settings
Sign Up to like & getrecommendations! Published in 2025 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s510926
Abstract: Objective This study aimed to standardize antimicrobial use in a hospital setting by implementing the Lean Six Sigma (LSS)-DMAIC model (Define, Measure, Analyze, Improve, Control), addressing the irrational use of antibacterial drugs. Methods A retrospective… read more here.
Keywords: antimicrobial use; hospital; use; standardize antimicrobial ... See more keywords
Novel Antibacterial Compounds and their Drug Targets - Successes and Challenges.
Sign Up to like & getrecommendations! Published in 2017 at "Current medicinal chemistry"
DOI: 10.2174/0929867323666161213102127
Abstract: Infectious diseases are one of the most important and urgent health problems in the world. According to the World Health Organization (WHO) statistics, infectious and parasitic diseases are a cause of about 16% of all… read more here.
Keywords: novel antibacterial; drug targets; antibacterial drugs; infectious diseases ... See more keywords
Natural bioactive compounds from medicinal plants as antibacterial drugs: mechanism insights and clinical perspectives.
Sign Up to like & getrecommendations! Published in 2022 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026622666220330011255
Abstract: The coevolution in microbes has generated major functional consequences leading bacteria to develop resistance to antibiotics. Indeed, bacterial strains have been able to develop and adapt to the action of antibiotics via several resistance mechanisms.… read more here.
Keywords: compounds medicinal; bioactive compounds; antibacterial drugs; plants antibacterial ... See more keywords
An LC-MS/MS method for the simultaneous determination of 18 antibacterial drugs in human plasma and its application in therapeutic drug monitoring
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1044234
Abstract: Antimicrobial resistance (AMR) is a major threat to global health due to the wide use of antibacterial drugs. Multiple studies show that the pharmacokinetic/pharmacodynamic (PK/PD) studies of antibiotics are an approach to prevent/delay AMR. The… read more here.
Keywords: human plasma; antibacterial drugs; therapeutic drug; drug monitoring ... See more keywords
Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11081105
Abstract: In the era of escalating antimicrobial resistance, the need for antibacterial drugs with novel or improved modes of action (MOAs) is a health concern of utmost importance. Adding or improving the chelating abilities of existing… read more here.
Keywords: chelation; chelation antibacterial; antibacterial drugs; nitroxoline cefiderocol ... See more keywords