Synthesis, antibacterial evaluation and preliminary mechanism study of novel isoquinoline‐3‐carboxylic acid derivatives containing an acylhydrazone disulfone moiety
Sign Up to like & getrecommendations! Published in 2025 at "Pest Management Science"
DOI: 10.1002/ps.8737
Abstract: Limitations in the use and availability of copper‐based fungicides and antibiotics has led to a scarcity of bactericidal agents. It is urgent to develop green bactericides with new modes‐of‐action and effective chemotypes. read more here.
Keywords: antibacterial evaluation; study novel; mechanism study; synthesis antibacterial ... See more keywords
In vitro Antibacterial Evaluation of 1,2,4-Triazole Compounds Containing Purine Moiety
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DOI: 10.1007/s10600-017-2217-7
Abstract: 9H-[1,2,4]Triazolo[4,3-g]purin-5-amine (2) was synthesized by reaction of 6-hydrazinyl-7H-purin-2-amine (1a) with formic acid under reflux conditions. Treating compound 1a in ethanol with CS2 in the presence of KOH yielded 5-amino-3H-[1,2,4]triazolo[4,3-g]purine-3-thione (3). The new synthesized compounds were… read more here.
Keywords: containing purine; evaluation triazole; triazole compounds; compounds containing ... See more keywords
Synthesis and antibacterial evaluation of diaminomaleonitrile-based azo-Schiff bases and 8,9-dihydro-7H-purine-6-carboxamides
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DOI: 10.1007/s11164-020-04175-y
Abstract: Some new DAMN-based Schiff base 6a–6g were synthesized via a condensation reaction of the corresponding azo dyes with 1-(2-amino-1,2-dicyanovinyl)-3-phenylurea. In continuation, facile synthesis of new 8,9-dihydro-7H-purine-6-carboxamide 7a–7g was reported via an efficient reaction of azo… read more here.
Keywords: synthesis antibacterial; dihydro purine; based azo; diaminomaleonitrile based ... See more keywords
Synthesis and antibacterial evaluation of (E)-1-(1H-indol-3-yl) ethanone O-benzyl oxime derivatives against MRSA and VRSA strains.
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DOI: 10.1016/j.bioorg.2021.105288
Abstract: Infections caused due to multidrug resistant organisms have emerged as a constant menace to human health. Even though numerous antibiotics are currently available for treating infectious diseases, a great number of bacterial strains have acquired… read more here.
Keywords: evaluation indol; indol ethanone; synthesis antibacterial; mrsa vrsa ... See more keywords
Design, Synthesis, Antibacterial Evaluation, Three-Dimensional Quantitative Structure-Activity Relationship, and Mechanism of Novel Quinazolinone Derivatives.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c07264
Abstract: Plant bacterial illnesses are common and cause dramatic damage to agricultural goods all over the world, yet there are few efficient bactericides to alleviate them at present. To discover novel antibacterial agents, two series of… read more here.
Keywords: design synthesis; mechanism; quinazolinone derivatives; antibacterial evaluation ... See more keywords
Design, Synthesis, and Antibacterial Evaluation of Novel Isoindolin-1-ones Derivatives Containing Piperidine Fragments.
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DOI: 10.1021/acs.jafc.3c09928
Abstract: A series of novel isoindoline-1-one derivatives containing piperidine moiety were designed and synthesized using natural compounds as raw materials, and their biological activities were tested for three bacterial and three fungal pathogens. These derivatives exhibited… read more here.
Keywords: containing piperidine; antibacterial evaluation; derivatives containing; synthesis antibacterial ... See more keywords
Total Synthesis and Antibacterial Evaluation of Lupinifolin and Its Natural Analogues.
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DOI: 10.1021/acs.jnatprod.4c00008
Abstract: In this study, lupinifolin (1) and its natural analogues, mundulin (2), minimiorin (3), khonklonginol H (4), flemichin D (5), and eriosemaone A (27), were obtained by chemical synthesis for the first time. Key steps involved… read more here.
Keywords: antibacterial evaluation; natural analogues; total synthesis; synthesis antibacterial ... See more keywords
Total synthesis and antibacterial evaluation of lupalbigenin and isolupalbigenin
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DOI: 10.1080/10286020.2024.2428794
Abstract: Abstract Lupalbigenin (1) is an antibacterial isoflavone isolated from Maclura cochinchinensis (Lour.) Corner (Moraceae). In this study, we achieved the first gram-scale synthesis of lupalbigenin (1) from commercially available genistein (2), with a yield of… read more here.
Keywords: evaluation lupalbigenin; antibacterial evaluation; total synthesis; synthesis antibacterial ... See more keywords
Synthesis and Antibacterial Evaluation of Benzofuran Based Di-1,2,3-triazoles
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DOI: 10.1134/s1070363218070265
Abstract: A series of novel benzofuran-1,2,3-triazole hybrid molecules are synthesized using the click chemistry approach. Structures of the synthesized compounds were assessed by IR, NMR, and mass spectroscopy. The tests of final products 10a–10l for their… read more here.
Keywords: synthesis antibacterial; evaluation benzofuran; based triazoles; chemistry ... See more keywords
Antibacterial Evaluation, In Silico Characters and Molecular Docking of Schiff Bases Derived from 5-aminopyrazoles
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DOI: 10.3390/molecules24173130
Abstract: A series of Schiff bases 14–25 were designed and synthesized for evaluation of their antibacterial properties against multi-drug resistant bacteria (MDRB). The antibacterial activities of Schiff bases 14–25 showed that most of the synthesized compounds… read more here.
Keywords: schiff; schiff bases; silico; antibacterial evaluation ... See more keywords
Extraction and antibacterial evaluation of marine AMPs against diabetic wound pathogens
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DOI: 10.7324/japs.2020.101112
Abstract: The need for an alternative wound dressing material with effective coatings using antimicrobial peptides (AMPs) from a marine fish (Carangoides malabaricus) was selected as the primary objective in the present research. The AMPs were extracted… read more here.
Keywords: dressing material; wound dressing; evaluation marine; marine amps ... See more keywords