Metallothionein 3-Zinc Axis Suppresses Caspase-11 Inflammasome Activation and Impairs Antibacterial Immunity
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DOI: 10.3389/fimmu.2021.755961
Abstract: Non-canonical inflammasome activation by mouse caspase-11 (or human CASPASE-4/5) is crucial for the clearance of certain gram-negative bacterial infections, but can lead to severe inflammatory damage. Factors that promote non-canonical inflammasome activation are well recognized,… read more here.
Keywords: antibacterial immunity; inflammasome activation; caspase inflammasome; caspase ... See more keywords