Expanding the antibacterial selectivity of polyether ionophore antibiotics through diversity focused semi-synthesis
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DOI: 10.1038/s41557-020-00601-1
Abstract: Polyether ionophores are complex natural products capable of transporting cations across biological membranes. Many polyether ionophores possess potent antimicrobial activity and a few selected compounds have the ability to target aggressive cancer cells. Nevertheless, ionophore… read more here.
Keywords: polyether ionophores; antibacterial selectivity; polyether; synthesis ... See more keywords
Biocompatible Cationic polypeptoids with antibacterial selectivity depending on hydrophobic carbon chain length
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Materials Chemistry B"
DOI: 10.1039/d3tb00643c
Abstract: The overuse of antibiotics has triggered a new infection crisis, and natural antimicrobial peptides (AMPs) have been extensively studied as an alternative to fight microorganisms. Polypeptoids, or polypeptide-biomimetics, offer similar... read more here.
Keywords: cationic polypeptoids; selectivity depending; depending hydrophobic; antibacterial selectivity ... See more keywords