Multi‐Mode Antibacterial Strategies Enabled by Gene‐Transfection and Immunomodulatory Nanoparticles in 3D‐Printed Scaffolds for Synergistic Exogenous and Endogenous Treatment of Infections
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202200096
Abstract: As research on refractory Staphylococcus aureus‐related implant infection intensifies, certain challenges remain, including low antibiotic concentrations within infected areas, immune escape achieved by intracellular bacteria, myeloid‐derived suppressor cells (MDSCs) inducing regional immunosuppression, and recurrence of… read more here.
Keywords: multi mode; antibacterial strategies; mode antibacterial; gene transfection ... See more keywords
Adhesive Composite Microspheres with Dual Antibacterial Strategies for Infected Wound Healing.
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DOI: 10.1002/smll.202301092
Abstract: Skin damage and infection pose a severe challenge to human health. Construction of a novel versatile dressing with good anti-infection and healing-promoting abilities is greatly expected. In this paper, nature-source-based composite microspheres with dual antibacterial… read more here.
Keywords: microspheres dual; wound healing; composite microspheres; antibacterial strategies ... See more keywords
Galleria mellonella as a consolidated in vivo model hosts: New developments in antibacterial strategies and novel drug testing
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DOI: 10.1080/21505594.2019.1621649
Abstract: ABSTRACT A greater ethical conscience, new global rules and a modified perception of ethical consciousness entail a more rigorous control on utilizations of vertebrates for in vivo studies. To cope with this new scenario, numerous… read more here.
Keywords: novel drug; antibacterial strategies; strategies novel; mellonella ... See more keywords
DXP Synthase Function in a Bacterial Metabolic Adaptation and Implications for Antibacterial Strategies
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DOI: 10.3390/antibiotics12040692
Abstract: Pathogenic bacteria possess a remarkable ability to adapt to fluctuating host environments and cause infection. Disturbing bacterial central metabolism through inhibition of 1-deoxy-d-xylulose 5-phosphate synthase (DXPS) has the potential to hinder bacterial adaptation, representing a… read more here.
Keywords: function; adaptation; metabolic adaptation; antibacterial strategies ... See more keywords
Algae Polyphenolic Compounds and Modern Antibacterial Strategies: Current Achievements and Immediate Prospects
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DOI: 10.3390/biomedicines8090342
Abstract: The increasing drug resistance of pathogenic microorganisms raises concern worldwide and necessitates the search for new natural compounds with antibacterial properties. Marine algae are considered a natural and attractive biotechnological source of novel antibiotics. The… read more here.
Keywords: algae polyphenolic; antibacterial strategies; polyphenolic compounds; compounds modern ... See more keywords