New Pqs Quorum Sensing System Inhibitor as an Antibacterial Synergist against Multidrug-Resistant Pseudomonas aeruginosa.
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DOI: 10.1021/acs.jmedchem.1c01781
Abstract: Development of new bacterial biofilm inhibitors as antibacterial synergists is an effective strategy to solve the resistance of Pseudomonas aeruginosa. In this paper, a series of 3-hydroxy-pyridin-4(1H)-ones were synthesized and evaluated, and the hit compound… read more here.
Keywords: antibacterial synergist; quorum sensing; pseudomonas aeruginosa; sensing system ... See more keywords