Dimeric lipo-α/sulfono-γ-AA hybrid peptides as broad-spectrum antibiotic agents.
Sign Up to like & getrecommendations! Published in 2021 at "Biomaterials science"
DOI: 10.1039/d0bm01955k
Abstract: There is an urgent need to develop novel antibiotic agents that can combat emerging drug resistance. Herein, we report the design and investigation of a class of short dimeric antimicrobial lipo-α/sulfono-γ-AA hybrid peptides. Some of… read more here.
Keywords: hybrid peptides; lipo sulfono; sulfono hybrid; dimeric lipo ... See more keywords
Plant Endophytes and Epiphytes: Burgeoning Sources of Known and "Unknown" Cytotoxic and Antibiotic Agents?
Sign Up to like & getrecommendations! Published in 2020 at "Planta medica"
DOI: 10.1055/a-1095-1111
Abstract: In the last 20 or so years, the influence of endophytes and, quite recently, epiphytes of plants upon the compounds found in those plants, which were usually assumed to be phytochemicals produced by the plant… read more here.
Keywords: plant; endophytes epiphytes; burgeoning sources; epiphytes burgeoning ... See more keywords
Peri-Prosthetic Knee Infection Management: Spacers Loaded with Two or Three Antibiotic Agents.
Sign Up to like & getrecommendations! Published in 2017 at "Surgical infections"
DOI: 10.1089/sur.2016.260
Abstract: BACKGROUND The purpose of this work was to compare pre-made antibiotic-loaded spacers with two commercially available antibiotic agents and custom-made cements with three antibiotic agents added. We evaluated: (a) the validity of our procedures, (b)… read more here.
Keywords: prosthetic knee; peri prosthetic; infection; three antibiotic ... See more keywords
Bacteriophages: A Therapy Concept against Multi-Drug–Resistant Bacteria
Sign Up to like & getrecommendations! Published in 2018 at "Surgical Infections"
DOI: 10.1089/sur.2018.184
Abstract: Abstract Bacteriophages (phages) are viruses that kill bacteria specifically but cannot infect other kinds of organisms. They have attracted new attention since the increasing antibiotic resistance developed into a global crisis. Phage therapy, a 100-year-old… read more here.
Keywords: medicine; phage; therapy concept; drug ... See more keywords
Duration of Antibiotic Therapy in Necrotizing Soft Tissue Infections: Shorter is Safe.
Sign Up to like & getrecommendations! Published in 2022 at "Surgical infections"
DOI: 10.1089/sur.2022.011
Abstract: Background: Early debridement improves outcome in necrotizing soft tissue infection (NSTI), but there is no consensus on duration of antimicrobial therapy. We recently changed practice to discontinue antibiotic agents early with a goal of 48… read more here.
Keywords: source control; duration; duration antibiotic; antibiotic agents ... See more keywords
Differences in Efficacy between Short- and Long-Course Antibiotic Agents for Joint Prosthesis Infection: A Systematic Review and Meta-Analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Surgical infections"
DOI: 10.1089/sur.2022.157
Abstract: Background: To evaluate systematically the failure rate of short versus long courses of antibiotic agents for prosthetic joint infections (PJIs). Methods: PubMed, Embase, and Cochrane Library databases were searched for controlled studies of short- and… read more here.
Keywords: meta analysis; antibiotic agents; long course; short long ... See more keywords
Bringing Eyelid Surgery in Line with International Guidelines Regarding Peri-Operative Antibiotic Agents: A Pilot Study.
Sign Up to like & getrecommendations! Published in 2022 at "Surgical infections"
DOI: 10.1089/sur.2022.217
Abstract: Background: International guidelines advise against prophylactic antimicrobial agents for primarily closed surgical incisions, but most oculoplastic surgeons report using chloramphenicol ointment. We evaluated baseline surgical site infection (SSI) rates in patients undergoing eyelid surgery who… read more here.
Keywords: eyelid surgery; surgery; international guidelines; infection ... See more keywords
Liquid Chromatography Mass Spectrometry Detection of Antibiotic Agents in Sputum from Persons with Cystic Fibrosis
Sign Up to like & getrecommendations! Published in 2020 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00927-20
Abstract: Antibiotic therapy is expected to impact host microbial communities considerably, yet many studies focused on microbiome and health are often confounded by limited information about antibiotic exposure. Given that antibiotics have diverse pharmacokinetic and antimicrobial… read more here.
Keywords: cystic fibrosis; fibrosis; mass spectrometry; chromatography mass ... See more keywords