Surfaces Containing Sharp Nanostructures Enhance Antibiotic Efficacy.
Sign Up to like & getrecommendations! Published in 2022 at "Nano letters"
DOI: 10.1021/acs.nanolett.2c02182
Abstract: The ever-increasing rate of medical device implantations is met by a proportionately high burden of implant-associated infections. To mitigate this threat, much research has been directed toward the development of antibacterial surface modifications by various… read more here.
Keywords: nanostructures enhance; surfaces containing; enhance antibiotic; sharp nanostructures ... See more keywords
Novel Antibiotic Testing Approaches Reveal Reduced Antibiotic Efficacy Against Shiga Toxin-Producing Escherichia coli O157:H7 Under Simulated Microgravity
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.03214
Abstract: As a foodborne and environmental pathogen, Shiga toxin-producing Escherichia coli O157:H7 could pose a health threat to immunocompromised astronauts during a space mission. In this study, novel approaches, including real-time testing and direct evaluation of… read more here.
Keywords: antibiotic efficacy; escherichia coli; coli o157; toxin producing ... See more keywords
Sodium Malonate Inhibits the AcrAB-TolC Multidrug Efflux Pump of Escherichia coli and Increases Antibiotic Efficacy
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11121409
Abstract: There is an urgent need to find novel treatments for combating multidrug-resistant bacteria. Multidrug efflux pumps that expel antibiotics out of cells are major contributors to this problem. Therefore, using efflux pump inhibitors (EPIs) is… read more here.
Keywords: sodium malonate; efficacy; antibiotic efficacy; multidrug efflux ... See more keywords