1472. Antibiotic De-escalation Compared with Continued Empirical Treatment in Non-Ventilated Hospital-Acquired Pneumonia
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DOI: 10.1093/ofid/ofy210.1302
Abstract: Abstract Background Antibiotic de-escalation is an important component of antimicrobial stewardship programs. Nosocomial pneumonia is the most common healthcare-associated infection with nonventilated hospital-acquired pneumonia (HAP) comprising the majority of cases. We aimed to compare antibiotic… read more here.
Keywords: treatment; hospital; continued empirical; empirical treatment ... See more keywords
Using Procalcitonin to Guide Antibiotic Escalation in Patients With Suspected Bacterial Infection: A New Application of Procalcitonin in the Intensive Care Unit
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DOI: 10.3389/fcimb.2022.844134
Abstract: Background Procalcitonin (PCT) is efficient in reducing antibiotic usage without increasing complications for its sensitivity and specificity in detecting bacterial infection. However, its role in guiding antibiotic-spectrum escalation has not been studied. This study was… read more here.
Keywords: suspected bacterial; escalation; infection; antibiotic escalation ... See more keywords
Antibiotic De-Escalation in Emergency General Surgery
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DOI: 10.3390/antibiotics11091148
Abstract: Background. Antibiotic treatment in emergency general surgery (EGS) is a major challenge for surgeons, and a multidisciplinary approach is necessary in order to improve outcomes. Intra-abdominal infections are at high risk of increased morbidity and… read more here.
Keywords: emergency general; surgery; escalation; general surgery ... See more keywords
Early Antibiotic Discontinuation or De-escalation in High-Risk Patients With AML With Febrile Neutropenia and Prolonged Neutropenia.
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DOI: 10.6004/jnccn.2021.7054
Abstract: BACKGROUND There is minimal data evaluating the safety of antibiotic de-escalation in patients with acute myeloid leukemia (AML) with fever and ongoing neutropenia. Therefore, this study evaluated antibiotic prescribing, infection-related outcomes, and patient outcomes of… read more here.
Keywords: escalation; patients aml; antibiotic escalation; group ... See more keywords