Analysis of Antibiotic Exposure and Early-Onset Neonatal Sepsis in Europe, North America, and Australia
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.43691
Abstract: Key Points Question What is the rate of exposure to antibiotics and the incidence of early-onset sepsis (EOS) and sepsis-associated mortality among late-preterm and full-term newborns? Findings In this cross-sectional study of 757 979 neonates born… read more here.
Keywords: sepsis; early onset; antibiotic exposure; analysis antibiotic ... See more keywords
The gut microbiota of silkworm are altered by antibiotic exposure
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13502
Abstract: In recent years, antibiotics have frequently been detected in soil, lakes, and rivers. Antibiotic residues in the environment may alter microbial structure and cause bacterial resistance, but their effect on interactions among host microbiota is… read more here.
Keywords: silkworm; antibiotic exposure; gut; gut microbiota ... See more keywords
Letter to the Editor: “Antibiotic exposure and risk of type 2 diabetes mellitus: a systematic review and meta-analysis”
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-022-18549-9
Abstract: We read with great interest the article by Zhou et al., in which the authors demonstrated (Zhou et al. 2021) the correlation between “Antibiotic exposure and risk of type 2 diabetes mellitus: a systematic review… read more here.
Keywords: antibiotic exposure; type diabetes; exposure risk; exposure ... See more keywords
Changes in microbiome diversity following beta-lactam antibiotic treatment are associated with therapeutic versus subtherapeutic antibiotic exposure in cystic fibrosis
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-38984-y
Abstract: In persons with cystic fibrosis (CF), decreased airway microbial diversity is associated with lower lung function. Conflicting data exist on the impact of short-term antibiotics for treatment of acute pulmonary exacerbations. However, whether differences in… read more here.
Keywords: lactam antibiotic; antibiotic exposure; diversity; beta lactam ... See more keywords
Childhood infection, antibiotic exposure and subsequent metabolic risk in adolescent and young adult Aboriginal Australians: practical implications.
Sign Up to like & getrecommendations! Published in 2019 at "Australian journal of primary health"
DOI: 10.1071/py18110
Abstract: There is now evidence linking antibiotic burden in infancy and subsequent risk factors for cardiometabolic disease. In this study we assessed the metabolic health of a community-based cohort of Aboriginal Australians aged 15-25 years and… read more here.
Keywords: antibiotic exposure; aboriginal australians; risk; childhood ... See more keywords
The association between early life antibiotic exposure and the gut resistome of young children: a systematic review
Sign Up to like & getrecommendations! Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2022.2120743
Abstract: ABSTRACT Antimicrobial resistance is a growing public health burden, but little is known about the effects of antibiotic exposure on the gut resistome. As childhood (0–5 years) represents a sensitive window of microbiome development and… read more here.
Keywords: antibiotic exposure; gut resistome; review; resistance ... See more keywords
Gut Microbial Diversity in Antibiotic-Naive Children After Systemic Antibiotic Exposure: A Randomized Controlled Trial
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Infectious Diseases"
DOI: 10.1093/cid/cix141
Abstract: Background Antibiotic exposure can alter the gut microbiome. We evaluate the effects of azithromycin on the gut microbiome diversity of children from an antibiotic-naive community in Niger. Methods A population-based sample of 80 children aged… read more here.
Keywords: diversity; group; gut microbiome; antibiotic exposure ... See more keywords
Center-level variability in broad-spectrum antibiotic prescribing for children undergoing hematopoietic cell transplantion for acute leukemia.
Sign Up to like & getrecommendations! Published in 2017 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofx163.623
Abstract: Abstract Background Antibiotic exposure after allogeneic hematopoietic cell transplant (HCT) is common. Exposure to specific classes of antibiotics after HCT has been associated with mortality, relapse and graft-vs.-host disease. Exploring differences in antibiotic utilization across… read more here.
Keywords: research; use; exposure; acute leukemia ... See more keywords
Impact of Procalcitonin-Guided Antibiotic Management on Antibiotic Exposure and Outcomes: Real-world Evidence
Sign Up to like & getrecommendations! Published in 2017 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofx213
Abstract: Abstract Background Delayed pathogen identification and nonspecific clinical findings make definitive decisions regarding antibiotics challenging. The stimuli of bacterial toxins and inflammation make procalcitonin (PCT) unique in its ability to differentiate bacterial infection from other… read more here.
Keywords: pct; antibiotic exposure; infection; antibiotic management ... See more keywords
Early Antibiotic Exposure in Low-resource Settings Is Associated With Increased Weight in the First Two Years of Life
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pediatric Gastroenterology and Nutrition"
DOI: 10.1097/mpg.0000000000001640
Abstract: Objectives: The potential growth-promoting effects of antibiotics are not well understood among undernourished children in environments with high pathogen exposure. We aimed to assess whether early antibiotic exposure duration and class were associated with growth… read more here.
Keywords: age; antibiotic exposure; low resource; resource settings ... See more keywords
Prevalence and determinants of antibiotic exposure in infants: A population‐derived Australian birth cohort study
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Paediatrics and Child Health"
DOI: 10.1111/jpc.13616
Abstract: The aim of this study was to describe antibiotic exposure in Australian infants during the first year of life, focusing on antibiotic class, indication, risk factors associated with exposure and comparison with international counterparts. read more here.
Keywords: exposure; study; prevalence determinants; exposure infants ... See more keywords