Ecology and evolution of antibiotic persistence.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in microbiology"
DOI: 10.1016/j.tim.2021.10.001
Abstract: Bacteria have at their disposal a battery of strategies to withstand antibiotic stress. Among these, resistance is a well-known mechanism, yet bacteria can also survive antibiotic attack by adopting a tolerant phenotype. In the case… read more here.
Keywords: evolution antibiotic; antibiotic persistence; ecology evolution; persistence ... See more keywords
Bacterial survivors: evaluating the mechanisms of antibiotic persistence.
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology"
DOI: 10.1099/mic.0.001266
Abstract: Bacteria withstand antibiotic onslaughts by employing a variety of strategies, one of which is persistence. Persistence occurs in a bacterial population where a subpopulation of cells (persisters) survives antibiotic treatment and can regrow in a… read more here.
Keywords: persistence; evaluating mechanisms; survivors evaluating; bacterial survivors ... See more keywords
Host Cell Oxidative Stress Promotes Intracellular Fluoroquinolone Persisters of Streptococcus pneumoniae
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DOI: 10.1128/spectrum.04364-22
Abstract: In S. pneumoniae, different mechanisms that counteract antibiotic effects have been described, such as vancomycin tolerance, heteroresistance to penicillin and fluoroquinolone resistance, which critically affect the therapeutic efficacy. Antibiotic persistence is a type of antibiotic… read more here.
Keywords: persistence; fluoroquinolone; oxidative stress; host ... See more keywords
Antibiotic persistence of intracellular Brucella abortus
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010635
Abstract: Background Human brucellosis caused by the facultative intracellular pathogen Brucella spp. is an endemic bacterial zoonosis manifesting as acute or chronic infections with high morbidity. Treatment typically involves a combination therapy of two antibiotics for… read more here.
Keywords: abortus; microscopy; brucella; treatment ... See more keywords
Link Between Antibiotic Persistence and Antibiotic Resistance in Bacterial Pathogens
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.900848
Abstract: Both, antibiotic persistence and antibiotic resistance characterize phenotypes of survival in which a bacterial cell becomes insensitive to one (or even) more antibiotic(s). However, the molecular basis for these two antibiotic-tolerant phenotypes is fundamentally different.… read more here.
Keywords: persistence; antibiotic resistance; culture conditions; persistence antibiotic ... See more keywords