Screening Criteria for Qualified Antibiotic Targets in Unmodified Gold Nanoparticles-Based Aptasensing.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b12796
Abstract: In designing unmodified gold nanoparticles-based aptasensing (uGA) assays for antibiotics, we find that some antibiotics can adsorb directly on gold nanoparticles (GNP) regardless of the presence of aptamers, which have been long overlooked in the… read more here.
Keywords: gold nanoparticles; antibiotic targets; unmodified gold; nanoparticles based ... See more keywords
Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c10819
Abstract: Phenotypic screening is a powerful approach to identify novel antibiotics, but elucidation of the targets responsible for the antimicrobial activity is often challenging in the case of compounds with a polypharmacological mode of action. Here,… read more here.
Keywords: reveals antibiotic; antibiotic targets; chemical proteomics; chemical ... See more keywords