Proteomic analysis of small intestinal epithelial cells in antibiotic-treated mice: Changes in drug transporters and metabolizing enzymes.
Sign Up to like & getrecommendations! Published in 2019 at "Drug metabolism and pharmacokinetics"
DOI: 10.1016/j.dmpk.2019.01.001
Abstract: Antibiotics act on bacterial flora originally present in the intestine, and changes in the intestinal flora have various effects on the host. This study investigated changes in the protein levels of drug transporters and metabolizing… read more here.
Keywords: antibiotic treated; transporters metabolizing; drug; metabolizing enzymes ... See more keywords
677 Evaluation of anti-PD1 efficacy in germ-free and antibiotic-treated SPF mice bearing MC38 tumors
Sign Up to like & getrecommendations! Published in 2020 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2020-sitc2020.0677
Abstract: Background Increasing evidence has indicated the important role of gut microbes in mediating normal and pathologic immune responses to cancer in both patients and animal models. There is growing effort in modulating microbiota composition to… read more here.
Keywords: antibiotic treated; spf mice; efficacy; germ free ... See more keywords
Ingestion of Lactobacillus intestinalis and Lactobacillus reuteri causes depression- and anhedonia-like phenotypes in antibiotic-treated mice via the vagus nerve
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-020-01916-z
Abstract: The brain–gut–microbiota axis plays a role in the pathogenesis of stress-related disorders such as depression. In this study, we examined the effects of fecal microbiota transplantation (FMT) in mice with antibiotic-treated microbiota depletion. The fecal… read more here.
Keywords: antibiotic treated; like phenotypes; treated mice; anhedonia like ... See more keywords
Collateral Damage in the Human Gut Microbiome - Blastocystis Is Significantly Less Prevalent in an Antibiotic-Treated Adult Population Compared to Non-Antibiotic Treated Controls
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.822475
Abstract: Antibiotics can drive the rapid loss of non-target, phylogenetically diverse microorganisms that inhabit the human gut. This so-called “collateral damage” has myriad consequences for host health and antibiotic mediated changes to the gut microbiota have… read more here.
Keywords: non antibiotic; antibiotic treated; blastocystis; collateral damage ... See more keywords