PROTAC antibiotics: the time is now
Sign Up to like & getrecommendations! Published in 2023 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2023.2178413
Abstract: ABSTRACT Introduction Novel antibiotics are needed to keep antibiotic resistance at bay and to improve treatment of the many drug-susceptible infections for which current therapies achieve poor cure rates. While revolutionizing human therapeutics, the concept… read more here.
Keywords: antibiotics time; protac antibiotics; protacs; drug ... See more keywords
Antibiotics Time Machines Are Hard to Build
Sign Up to like & getrecommendations! Published in 2017 at "Notices of the American Mathematical Society"
DOI: 10.1090/noti1590
Abstract: Could we somehow go back in time before bacteria developed resistance to antibiotics? Mira et al. famously cast antibiotics resistance as an optimization problem called the “antibiotics time machine.” We show that such a strategy… read more here.
Keywords: antibiotics time; time; genotype; time machine ... See more keywords