Potential Use of Supercharging Agents for Improved Mass Spectrometric Analysis of Monoclonal Antibodies and Antibody-Drug Conjugates.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.2c00008
Abstract: The addition of supercharging (SC) reagents in electrospray ionization coupled mass spectrometry (ESI-MS) has demonstrated several advantages for protein analysis such as reduced required mass range of the instrument, narrowed charge-state distribution, increased sensitivity, and… read more here.
Keywords: antibodies antibody; analysis; potential use; drug ... See more keywords
The Antibody Registry: ten years of registering antibodies
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac927
Abstract: Abstract Antibodies are ubiquitous key biological research resources yet are tricky to use as they are prone to performance issues and represent a major source of variability across studies. Understanding what antibody was used in… read more here.
Keywords: antibody registry; antibodies antibody; registry ten; registry ... See more keywords
Ion Channel Targeting with Antibodies and Antibody Fragments for Cancer Diagnosis
Sign Up to like & getrecommendations! Published in 2019 at "Antibodies"
DOI: 10.3390/antib8020033
Abstract: The antibody era has greatly impacted cancer management in recent decades. Indeed, antibodies are currently applied for both cancer diagnosis and therapy. For example, monoclonal antibodies are the main constituents of several in vitro diagnostics,… read more here.
Keywords: cancer; antibodies antibody; cancer diagnosis; antibody fragments ... See more keywords