Abstract 5199: B7-H3 & PD-L1 double-humanized BALB/c mouse: a novel animal model for preclinical studies of human B7-H3 antibodies or bispecific antibodies
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DOI: 10.1158/1538-7445.am2023-5199
Abstract: Immune checkpoint molecule B7-H3, also known as CD276, is a member of the B7-CD28 family of immunomodulatory proteins. It is a type I membrane protein with sequence similarities to the extracellular domain of programmed death-ligand… read more here.
Keywords: double humanized; bispecific antibodies; mouse; antibodies bispecific ... See more keywords