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Published in 2018 at "Critical reviews in oncology/hematology"
DOI: 10.1016/j.critrevonc.2018.05.002
Abstract: Antinuclear antibodies (ANAs) are a spectrum of autoantibodies targeted to various nuclear and cytoplasmic components of the cells. They are very useful as serological markers for different autoimmune disease, like systemic lupus erythematosus (SLE), Sjögren's…
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Keywords:
antinuclear antibodies;
antibodies cancer;
cancer;
cancer literature ... See more keywords
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Published in 2022 at "Rheumatology"
DOI: 10.1093/rheumatology/keac614
Abstract: OBJECTIVE To define the clinical phenotype of SSc patients with antibodies against Sjogren's syndrome (SS)/scleroderma autoantigen 1 (SSSCA1), and to examine the association between these antibodies and cancer in SSc patients. METHODS We conducted a…
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Keywords:
ssc;
antibodies cancer;
anti sssca1;
association ... See more keywords
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Published in 2023 at "Immunology"
DOI: 10.1111/imm.13636
Abstract: Despite the clinical success of monoclonal and bispecific antibodies, there are still limitations in the therapeutic effect of malignant tumors, such as low response rate, treatment resistance, etc., inspiring the exploration of trispecific antibodies (TsAbs).…
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Keywords:
immunology;
trispecific antibodies;
cancer immunotherapy;
antibodies cancer ... See more keywords
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Published in 2020 at "Antibodies"
DOI: 10.3390/antib9030034
Abstract: Monoclonal antibody-based immunotherapy is now considered to be a main component of cancer therapy, alongside surgery, radiation, and chemotherapy. Monoclonal antibodies possess a diverse set of clinically relevant mechanisms of action. In addition, antibodies can…
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Keywords:
tumor;
monoclonal antibodies;
antibodies cancer;
cancer ... See more keywords
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Published in 2022 at "Cancers"
DOI: 10.3390/cancers14061454
Abstract: Simple Summary Monoclonal antibodies (mAbs) have the ability to specifically target tumor-cell antigens. This unique property has led to their use in the delivery of radioisotopes to tumor sites (scintigraphic imaging and radioimmunotherapy (RIT)). The…
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Keywords:
radiolabeled antibodies;
therapy;
solid tumors;
treatment ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232314589
Abstract: The growing understanding of the molecular mechanisms of carcinogenesis accelerated the development of monoclonal therapeutic antibodies to specifically target multiple cancer pathways. Recombinant protein therapeutics now constitute a large proportion of yearly approved medicines. Oncology,…
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Keywords:
therapeutic antibodies;
cancer treatment;
antibodies cancer;
cancer ... See more keywords
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Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14061243
Abstract: Immunotherapy has redefined the treatment of cancer patients and it is constantly generating new advances and approaches. Among the multiple options of immunotherapy, bispecific antibodies (bsAbs) represent a novel thoughtful approach. These drugs integrate the…
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Keywords:
bispecific antibodies;
antibodies cancer;
novel response;
cancer ... See more keywords