Modulating tyrosine sulfation of recombinant antibodies in CHO cell culture by host selection and sodium chlorate supplementation
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DOI: 10.1002/biot.202100142
Abstract: Tyrosine sulfation is a post‐translational modification found on many surface receptors and plays an important role in cell‐cell and cell‐matrix interactions. However, tyrosine sulfation of therapeutic antibodies has only been reported very recently. Because of… read more here.
Keywords: tyrosine sulfation; modulating tyrosine; sulfation; recombinant antibodies ... See more keywords