Pre-targeting amyloid-β with antibodies for potential molecular imaging of Alzheimer's disease.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc06850h
Abstract: With the aim of developing the concept of pretargeted click chemistry for the diagnosis of Alzheimer's disease two antibodies specific for amyloid-β were modified to incorporate trans-cyclooctene functional groups. Two bis(thiosemicarbazone) compounds with pendant 1,2,4,5-tetrazine… read more here.
Keywords: disease; alzheimer disease; antibodies potential; amyloid antibodies ... See more keywords