New monoclonal antibodies that recognize an unglycosylated, conserved, extracellular region of CD44 in vitro and in vivo, and can block tumorigenesis
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DOI: 10.1371/journal.pone.0250175
Abstract: CD44 is a transmembrane glycoprotein that binds to hyaluronic acid, plays roles in a number of cellular processes and is expressed in a variety of cell types. It is up-regulated in stem cells and cancer.… read more here.
Keywords: tumorigenesis; monoclonal antibodies; anti cd44; cd44 ... See more keywords
How Enzymes, Proteins, and Antibodies Recognize Extended DNAs; General Regularities
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DOI: 10.3390/ijms22031369
Abstract: X-ray analysis cannot provide quantitative estimates of the relative contribution of non-specific, specific, strong, and weak contacts of extended DNA molecules to their total affinity for enzymes and proteins. The interaction of different enzymes and… read more here.
Keywords: general regularities; enzymes proteins; dna; proteins antibodies ... See more keywords