Influence of Label and Charge Density on the Association of the Therapeutic Monoclonal Antibodies Trastuzumab and Cetuximab Conjugated to Anionic Fluorophores
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DOI: 10.1002/cbic.201600299
Abstract: The design of bright and functional dye–protein conjugates requires hydrophilic and stable fluorophores with high molar absorption coefficients and high fluorescence quantum yields, which must not be prone to dimerization, as well as conservation of… read more here.
Keywords: protein; trastuzumab cetuximab; charge; association ... See more keywords