[Antibodies as treatment option in older adults].
Sign Up to like & getrecommendations! Published in 2018 at "Zeitschrift fur Gerontologie und Geriatrie"
DOI: 10.1007/s00391-017-1352-x
Abstract: Monoclonal antibodies are already used for many different clinical indications. Besides oncology and rheumatology, denosumab is the only antibody that is currently prescribed in older adults with osteoporosis; however, apart from osteoporosis there might be… read more here.
Keywords: treatment option; antibodies treatment; oncology; rheumatology ... See more keywords
Bispecific Antibodies for the Treatment of Acute Myeloid Leukemia
Sign Up to like & getrecommendations! Published in 2018 at "Current Hematologic Malignancy Reports"
DOI: 10.1007/s11899-018-0472-8
Abstract: Purpose of reviewBispecific antibodies combine antigen recognition sites from two or more antibodies into a single construct allowing simultaneous binding to multiple targets. Bispecific antibodies exist which can redirect immune effector cells against acute myeloid… read more here.
Keywords: myeloid leukemia; treatment; antibodies treatment; bispecific antibodies ... See more keywords
Bispecific antibodies for the treatment of haemophilia A.
Sign Up to like & getrecommendations! Published in 2021 at "Expert opinion on biological therapy"
DOI: 10.1080/14712598.2021.1940133
Abstract: INTRODUCTION : Emicizumab is a bispecific antibody exerting cofactor function of FVIIIa irrespective of the presence of FVIII inhibitors. Long-term data of phase 1/2 and phase 3 studies have been accumulated. Various questions such as… read more here.
Keywords: treatment; antibodies treatment; treatment haemophilia; bispecific antibodies ... See more keywords
Questionable Efficacy of Therapeutic Antibodies in the Treatment of Anthrax
Sign Up to like & getrecommendations! Published in 2019 at "mSphere"
DOI: 10.1128/msphere.00282-19
Abstract: Inhalational anthrax caused by Bacillus anthracis, a spore-forming Gram-positive bacterium, is a highly lethal infection. Antibodies targeting the protective antigen (PA) binding component of the toxins have recently been authorized as an adjunct to antibiotics,… read more here.
Keywords: questionable efficacy; antibodies treatment; efficacy therapeutic; inhalational anthrax ... See more keywords
The efficacy and safety of anti-PD-1/PD-L1 antibodies for treatment of advanced or refractory cancers: A meta-analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e23075
Abstract: e23075Background: Immunotherapy based on anti-PD-1 (Programmed death 1)/PD-L1 (PD-1 Ligand 1) antibodies have achieved significant successes from bench to clinic. In this study, we systematically e... read more here.
Keywords: advanced refractory; efficacy safety; treatment advanced; safety anti ... See more keywords
Monoclonal Antibodies for the Treatment of Cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Anticancer research"
DOI: 10.21873/anticanres.12040
Abstract: The ability of cancer cells to evade the immune system is one of the most deadly characteristics of the majority of malignant tumours. Accordingly, the recent development of antibodies which target tumor cell evasion of… read more here.
Keywords: monoclonal antibodies; treatment; antibodies treatment; treatment cancer ... See more keywords
Application of recombinant antibodies for treatment of Clostridioides difficile infection: Current status and future perspective
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.972930
Abstract: Clostridioides difficile (C. difficile), known as the major cause of antibiotic-associated diarrhea, is regarded as one of the most common healthcare-associated bacterial infections worldwide. Due to the emergence of hypervirulent strains, development of new therapeutic… read more here.
Keywords: application; clostridioides difficile; antibodies treatment; difficile infection ... See more keywords
Therapeutic Antibodies for the Treatment of Respiratory Tract Infections—Current Overview and Perspectives
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DOI: 10.3390/vaccines9020151
Abstract: Respiratorytract infections (RTIs) are frequent and life-threatening diseases, accounting for several millions of deaths worldwide. RTIs implicate microorganisms, including viruses (influenza virus, coronavirus, respiratory syncytial virus (RSV)), bacteria (Pseudomonas aeruginosa, Streptococcus pneumoniae, Staphylococcus aureus and… read more here.
Keywords: therapeutic antibodies; respiratory tract; treatment; antibodies treatment ... See more keywords