Articles with "antibody assessment" as a keyword



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PDGFRα monoclonal antibody: Assessment of toxicity in juvenile mice administered a murine surrogate antibody of olaratumab

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Published in 2023 at "Birth Defects Research"

DOI: 10.1002/bdr2.2169

Abstract: Olaratumab (Lartruvo™) is a recombinant human IgG1 monoclonal antibody that specifically binds PDGFRα. In order to support use of Lartruvo in pediatric patients, a definitive juvenile animal study in neonatal mice was conducted with a… read more here.

Keywords: pdgfr monoclonal; monoclonal antibody; antibody assessment; mice ... See more keywords