Primary antibody deficiencies represent an underestimated comorbidity in asthma patients: efficacy of immunoglobulin replacement therapy in asthma control
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Asthma"
DOI: 10.1080/02770903.2022.2140435
Abstract: Abstract Objective Primary antibody deficiencies (PAD) are an underestimated comorbidity in asthma and its treatment could improve disease control. Methods a retrospective cohort of asthmatics, affected by IgG subclass deficiency or unclassified antibody deficiency and… read more here.
Keywords: primary antibody; antibody deficiencies; control; asthma ... See more keywords
Appropriate lung management in patients with primary antibody deficiencies
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Respiratory Medicine"
DOI: 10.1080/17476348.2019.1641085
Abstract: ABSTRACT Introduction: Human primary immunodeficiency diseases (PIDs) include a broad spectrum of more than 350 disorders, involving different branches of the immune system and classified as ‘rare diseases.’ Predominantly antibody deficiencies (PADs) represent more than… read more here.
Keywords: appropriate lung; primary antibody; antibody deficiencies; lung management ... See more keywords
Known and potential molecules associated with altered B cell development leading to predominantly antibody deficiencies
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Allergy and Immunology"
DOI: 10.1111/pai.13589
Abstract: Predominantly antibody deficiencies (PADs) encompass a heterogeneous group of disorders characterized by low immunoglobulin serum levels in the presence or absence of peripheral B cells. Clinical presentation of affected patients may include recurrent respiratory and… read more here.
Keywords: cell development; predominantly antibody; antibody deficiencies; affected patients ... See more keywords
SIAE Rare Variants in Juvenile Idiopathic Arthritis and Primary Antibody Deficiencies
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Immunology Research"
DOI: 10.1155/2017/1514294
Abstract: Sialic acid acetylesterase (SIAE) deficiency was suggested to lower the levels of ligands for sialic acid-binding immunoglobulin-like receptors, decreasing the threshold for B-cell activation. In humans, studies of rare heterozygous loss-of-function mutations in SIAE gene… read more here.
Keywords: juvenile idiopathic; siae rare; idiopathic arthritis; rare variants ... See more keywords
The broad spectrum of lung diseases in primary antibody deficiencies
Sign Up to like & getrecommendations! Published in 2018 at "European Respiratory Review"
DOI: 10.1183/16000617.0019-2018
Abstract: Human primary immunodeficiency diseases (PIDs) represent a heterogeneous group of more than 350 disorders. They are rare diseases, but their global incidence is more relevant than generally thought. The underlying defect may involve different branches… read more here.
Keywords: antibody deficiencies; lung diseases; broad spectrum; primary antibody ... See more keywords
A Critical View of Specific Antibody Deficiencies
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DOI: 10.3389/fimmu.2019.00986
Abstract: In thisopinion manuscript the author postulates that the present definition of Specific Antibody Deficiency (SAD) needs to be revised and expanded. It is presently defined as a syndrome of low IgG antibody responses to purified… read more here.
Keywords: specific antibody; antibody; critical view; antibody deficiencies ... See more keywords
Salmonella Typhi Vaccination Response as a Tool for the Stratification of Risk in Patients with Predominantly Antibody Deficiencies
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12102423
Abstract: Predominantly antibody deficiencies are the most frequent type of primary immunodeficiency (PID). Diagnosis requires evaluation of the immune function by distinguishing the presence or absence of a response against polysaccharide antigens. Salmonella enterica serovar Typhi-based… read more here.
Keywords: tool; antibody deficiencies; vaccination; vaccination response ... See more keywords
Clinical Outcome of Coronavirus Disease 2019 in Patients with Primary Antibody Deficiencies
Sign Up to like & getrecommendations! Published in 2023 at "Pathogens"
DOI: 10.3390/pathogens12010109
Abstract: In 2019, the novel coronavirus, SARS-CoV-2, caused a worldwide pandemic, affecting more than 630 million individuals and causing 6.5 million deaths. In the general population, poorer outcomes have been associated with older age, chronic lung… read more here.
Keywords: primary antibody; antibody deficiencies; disease; coronavirus ... See more keywords
Coronavirus Disease 2019 and Primary Antibody Deficiencies. Comment on Milota et al. Clinical Outcome of Coronavirus Disease 2019 in Patients with Primary Antibody Deficiencies. Pathogens 2023, 12, 109
Sign Up to like & getrecommendations! Published in 2023 at "Pathogens"
DOI: 10.3390/pathogens12040532
Abstract: We have read the article titled 'Clinical Outcome of Coronavirus Disease 2019 in Patients with Primary Antibody Deficiencies' by Milota et al. with great interestl [...]. read more here.
Keywords: disease 2019; antibody deficiencies; coronavirus disease; primary antibody ... See more keywords
Cytokine Response Following SARS-CoV-2 Antigen Stimulation in Patients with Predominantly Antibody Deficiencies
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15051146
Abstract: Predominantly antibody deficiencies (PADs) are inborn disorders characterized by immune dysregulation and increased susceptibility to infections. Response to vaccination, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), may be impaired in these patients, and studies… read more here.
Keywords: antibody deficiencies; stimulation; cytokine response; predominantly antibody ... See more keywords