Development of disulfide-stabilized Fabs for targeting of antibody-directed nanotherapeutics
Sign Up to like & getrecommendations! Published in 2022 at "mAbs"
DOI: 10.1080/19420862.2022.2083466
Abstract: ABSTRACT Antibody-directed nanotherapeutics (ADNs) represent a promising delivery platform for selective delivery of an encapsulated drug payload to the site of disease that improves the therapeutic index. Although both single-chain Fv (scFv) and Fab antibody… read more here.
Keywords: directed nanotherapeutics; antibody directed; development disulfide; disulfide stabilized ... See more keywords
Cutaneous Lymphoma and Antibody-Directed Therapies
Sign Up to like & getrecommendations! Published in 2023 at "Antibodies"
DOI: 10.3390/antib12010021
Abstract: The introduction of monoclonal antibodies such as rituximab to the treatment of cancer has greatly advanced the treatment scenario in onco-hematology. However, the response to these agents may be limited by insufficient efficacy or resistance.… read more here.
Keywords: cutaneous lymphoma; antibody directed; lymphoma antibody; antibody ... See more keywords