Therapeutic Antibody Discovery in Infectious Diseases Using Single-Cell Analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-0502-3_8
Abstract: Since the discovery of mouse hybridoma technology by Kohler and Milstein in 1975, significant progress has been made in monoclonal antibody production. Advances in B cell immortalization and phage display technologies have generated a myriad… read more here.
Keywords: single cell; cell analysis; antibody discovery; cell ... See more keywords
Expediting Antibody Discovery with a Cell and Bead Multiplexed Competition Assay
Sign Up to like & getrecommendations! Published in 2018 at "SLAS Discovery"
DOI: 10.1177/2472555218776308
Abstract: With advances in molecular engineering and humanization, monoclonal antibodies are one of the fastest-growing classes of biopharmaceuticals. During antibody discovery, antibody from hybridoma or primary B-cell supernatants is screened for the desired binding characteristics, and… read more here.
Keywords: antibody discovery; cell bead; antibody; competition assay ... See more keywords