Use of IMGT® Databases and Tools for Antibody Engineering and Humanization.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8648-4_3
Abstract: IMGT®, the international ImMunoGeneTics information system® ( http://www.imgt.org ), was created in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS) to manage the huge diversity of the antigen receptors, immunoglobulins (IG) or antibodies, and… read more here.
Keywords: imgt databases; antibody engineering; imgt; databases tools ... See more keywords
mmCSM-AB: guiding rational antibody engineering through multiple point mutations
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DOI: 10.1093/nar/gkaa389
Abstract: Abstract While antibodies are becoming an increasingly important therapeutic class, especially in personalized medicine, their development and optimization has been largely through experimental exploration. While there have been many efforts to develop computational tools to… read more here.
Keywords: point mutations; antibody engineering; antibody; multiple point ... See more keywords