Construction of Human Naïve Antibody Gene Libraries.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8648-4_4
Abstract: Size and variability often represent an obstacle in generating an effective antibody gene library for the detection of an abundant repertoire of antigens. Therefore, optimizing the construction of a large library is essential for the… read more here.
Keywords: construction human; biology; antibody gene;
State of play and clinical prospects of antibody gene transfer
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-017-1234-4
Abstract: Recombinant monoclonal antibodies (mAbs) are one of today’s most successful therapeutic classes in inflammatory diseases and oncology. A wider accessibility and implementation, however, is hampered by the high product cost and prolonged need for frequent… read more here.
Keywords: gene transfer; clinical prospects; antibody gene;